Background Asymmetric NG, NG-dimethylarginine (ADMA) is an endogenous inhibitor of
endothelial nitric oxide (NO) synthase and its plasma concentration is elevated in patients …

Background: Obstructive sleep apnoea (OSA) is a common and potentially reversible cause
of systemic hypertension. The mechanisms whereby OSA leads to hypertension and the …

Purpose We investigated whether the nasal continuous positive airway pressure (nCPAP)
could have impacts on impaired vascular functions and serum cardiovascular risk factors in …

BACKGROUND Reduced endothelium dependent vasodilation has been reported in
patients with obstructive sleep apnoea (OSA) but direct measurements of the most potent …

Epidemiological studies have implicated obstructive sleep apnea (OSA) as an independent
comorbid factor in cardiovascular and cerebrovascular diseases. The recurrent episodes of …

Background Several studies suggest an increase of oxidative stress and a reduction of
endothelial function in obstructive sleep apnoea syndrome (OSAS). We assessed the …

STUDY OBJECTIVES: The process of intermittent hypoxia-reoxygenation produces airway
inflammation and endothelial dysfunction that favors the development of cardiovascular …

Impaired endothelium-dependent vascular relaxation is a prognostic marker of
atherosclerosis and cardiovascular disease. We evaluated endothelium-dependent flow …

Background The increase in peripheral chemoreflex sensitivity in patients with obstructive
sleep apnea (OSA) is associated with activation of autonomic nervous system and …

Asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) are
endogenous inhibitors of nitric oxide (NO) synthesis, and play a critical role in the process of …