[HTML][HTML] CRISPR-based diagnostics
MM Kaminski, OO Abudayyeh, JS Gootenberg… - Nature Biomedical …, 2021 - nature.com
The accurate and timely diagnosis of disease is a prerequisite for efficient therapeutic
intervention and epidemiological surveillance. Diagnostics based on the detection of nucleic …
intervention and epidemiological surveillance. Diagnostics based on the detection of nucleic …
Advances in clustered, regularly interspaced short palindromic repeats (CRISPR)-based diagnostic assays assisted by micro/nanotechnologies
Clustered, regularly interspaced short palindromic repeats (CRISPR)-based diagnoses,
derived from gene-editing technology, have been exploited for less than 5 years and are …
derived from gene-editing technology, have been exploited for less than 5 years and are …
Challenges and opportunities for clustered regularly interspaced short palindromic repeats based molecular biosensing
Clustered regularly interspaced short palindromic repeats, CRISPR, has recently emerged
as a powerful molecular biosensing tool for nucleic acids and other biomarkers due to its …
as a powerful molecular biosensing tool for nucleic acids and other biomarkers due to its …
CRISPR‐Cas Biochemistry and CRISPR‐Based Molecular Diagnostics
Polymerase chain reaction (PCR)‐based nucleic acid testing has played a critical role in
disease diagnostics, pathogen surveillance, and many more. However, this method requires …
disease diagnostics, pathogen surveillance, and many more. However, this method requires …
The CRISPR–Cas toolbox for analytical and diagnostic assay development
Y Tang, L Gao, W Feng, C Guo, Q Yang, F Li… - Chemical Society …, 2021 - pubs.rsc.org
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-
associated (Cas) systems have revolutionized biological and biomedical sciences in many …
associated (Cas) systems have revolutionized biological and biomedical sciences in many …
CRISPR systems for COVID-19 diagnosis
The emergence of the new coronavirus 2019 (COVID-19) was first seen in December 2019,
which has spread rapidly and become a global pandemic. The number of cases of COVID …
which has spread rapidly and become a global pandemic. The number of cases of COVID …
Aptamer-linked CRISPR/Cas12a-based immunoassay
H Li, M Li, Y Yang, F Wang, F Wang, C Li - Analytical Chemistry, 2021 - ACS Publications
The clustered regularly interspaced short palindromic repeat (CRISPR)/Cas system has
shown great promising applications in the area of nucleic acid biosensing. However …
shown great promising applications in the area of nucleic acid biosensing. However …
Integrating CRISPR/Cas within isothermal amplification for point-of-Care Assay of nucleic acid
L Zhang, H Jiang, Z Zhu, J Liu, B Li - Talanta, 2022 - Elsevier
Nucleic acid detection technology is now widely used in scientific research and clinical
testing, such as infectious and genetic diseases screening, molecular diagnosis of tumors …
testing, such as infectious and genetic diseases screening, molecular diagnosis of tumors …
Harnessing CRISPR effectors for infectious disease diagnostics
RP Bhattacharyya, SG Thakku… - ACS infectious diseases, 2018 - ACS Publications
Nucleic acid detection is an important method for pathogen identification but can be
expensive, have variable sensitivity and specificity, and require substantial infrastructure …
expensive, have variable sensitivity and specificity, and require substantial infrastructure …
Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives
Rapid and accurate molecular diagnosis is a prerequisite for precision medicine, food
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …