Although nanomedicine have greatly developed and human life span has been extended,
we have witnessed the soared incidence of central nervous system (CNS) diseases …

The blood-brain barrier (BBB), a dynamic and complex barrier formed by endothelial cells,
can impede the entry of unwanted substances–pathogens and therapeutic molecules alike …

The complex physiological and pathological conditions form barriers against efficient drug
delivery. Cell penetrating peptides (CPPs), a class of short peptides which translocate drugs …

The challenge of effectively delivering therapeutic agents to brain has led to an entire field of
active research devoted to overcome the blood brain barrier (BBB) and efficiently deliver …

Cell‐penetrating peptides (CPPs) can transport various cargoes through membranes of live
cells. Since the first generations of CPPs suffered from insufficient cell and tissue selectivity …

Cancer has become one of the leading causes of mortality globally. The major challenges of
conventional cancer therapy are the failure of most chemotherapeutic agents to accumulate …

The hydrophilic nature of peptides and proteins renders them impermeable to cell
membranes. Thus, in order to successfully deliver peptide and protein-based therapeutics …

Efficient delivery of therapeutic and diagnostic molecules to the cells and tissues is a difficult
challenge. The cellular membrane is very effective in its role as a selectively permeable …

Nearly one in six people worldwide suffer from disorders of the central nervous system
(CNS). There is an urgent need for effective strategies to improve the success rates in CNS …

During the past decades, functionalized nano-systems were believed in holding the bright
future of the nanomaterials in biomedical applications. Due to their excellent …