[HTML][HTML] Hydrogen sulfide reduces ischemia and reperfusion injury in neuronal cells in a dose-and time-dependent manner

S Scheid, M Goeller, W Baar, J Wollborn… - International journal of …, 2021 - mdpi.com
Background: The ischemia-reperfusion injury (IRI) of neuronal tissue, such as the brain and
retina, leads to possible cell death and loss of function. Current treatment options are limited …

[HTML][HTML] Inhalative as well as Intravenous Administration of H2S Provides Neuroprotection after Ischemia and Reperfusion Injury in the Rats' Retina

S Scheid, M Goeller, W Baar, J Wollborn… - International journal of …, 2022 - mdpi.com
Background: Neuronal ischemia-reperfusion injury (IRI), such as it can occur in glaucoma or
strokes, is associated with neuronal cell death and irreversible loss of function of the affected …

Hydrogen sulfide protects the brain against ischemic reperfusion injury in a transient model of focal cerebral ischemia

S Gheibi, N Aboutaleb, M Khaksari… - Journal of Molecular …, 2014 - Springer
Abstract Hydrogen sulfide (H 2 S), a well-known toxic gas, is regarded as endogenous
neuromodulator and plays multiple roles in the central nervous system under physiological …

[HTML][HTML] Vascular protection of hydrogen sulfide on cerebral ischemia/reperfusion injury in rats

JY Wen, M Wang, YN Li, HH Jiang, XJ Sun… - Frontiers in …, 2018 - frontiersin.org
This study was undertaken to demonstrate the vascular protection of exogenous and
endogenous hydrogen sulfide (H2S) on cerebral ischemia/reperfusion (I/R) injury. The effect …

[HTML][HTML] Hydrogen sulfide attenuates neuroinflammation by inhibiting the NLRP3/Caspase-1/GSDMD pathway in retina or brain neuron following rat ischemia …

KL Yang, WH Li, YJ Liu, YJ Wei, YK Ren, CD Mai… - Brain Sciences, 2022 - mdpi.com
Gasdermin D-executing pyroptosis mediated by NLRP3 inflammasomes has been
recognized as a key pathogenesis during stroke. Hydrogen sulfide (H2S) could protect CNS …

[HTML][HTML] Proteomics reveals the potential protective mechanism of hydrogen sulfide on retinal ganglion cells in an ischemia/reperfusion injury animal model

H Liu, N Perumal, C Manicam, K Mercieca, V Prokosch - Pharmaceuticals, 2020 - mdpi.com
Glaucoma is the leading cause of irreversible blindness and is characterized by progressive
retinal ganglion cell (RGC) degeneration. Hydrogen sulfide (H2S) is a potent …

Protective effect of hydrogen sulfide on cerebral ischemia–reperfusion injury

G Deng, M Muqadas, S Adlat, H Zheng, G Li… - Cellular and molecular …, 2023 - Springer
The brain is the most sensitive organ to hypoxia in the human body. Hypoxia in the brain will
lead to damage to local brain tissue. When the blood supply of ischemic brain tissue is …

Thiosulfate mediates cytoprotective effects of hydrogen sulfide against neuronal ischemia

E Marutani, M Yamada, T Ida, K Tokuda… - Journal of the …, 2015 - Am Heart Assoc
Background Hydrogen sulfide (H2S) exhibits protective effects in various disease models
including cerebral ischemia–reperfusion (I/R) injury. Nonetheless, mechanisms and identity …

Exogenous hydrogen sulfide protects against global cerebral ischemia/reperfusion injury via its anti-oxidative, anti-inflammatory and anti-apoptotic effects in rats

J Yin, C Tu, J Zhao, D Ou, G Chen, Y Liu, X Xiao - Brain research, 2013 - Elsevier
The present study was undertaken to study the effects of exogenous hydrogen sulfide (H2S)
on global cerebral ischemia–reperfusion (I/R) and the underlying mechanisms. After a 24h …

Hydrogen sulfide prevents OGD/R-induced apoptosis by suppressing the phosphorylation of p38 and secretion of IL-6 in PC12 cells

C Li, Y Liu, P Tang, P Liu, C Hou, X Zhang, L Chen… - …, 2016 - journals.lww.com
Abstract Hydrogen sulfide (H 2 S), a well-known endogenous mediator, has been shown to
exert protective effects against neuronal damage caused by brain ischemia, but the …