Antimicrobial resistance (AMR) gene cassettes comprise an AMR gene flanked by short
recombination sites (attI x attC or attC x attC). Integrons are genetic elements able to …

Mobile genetic elements contribute to the emergence and spread of multidrug-resistant
bacteria by enabling the horizontal transfer of acquired antibiotic resistance among different …

Background Integrons, especially the class 1 integrons, are major contributors to the
acquisition and dissemination of antibiotic resistance genes (ARGs). However …

Abstract Objectives In Pseudomonas aeruginosa, the bla GES-6 carbapenemase gene was
previously associated with an In1076 class I integron. Here, we conducted a genome-based …

IncQ-type plasmids have become important vectors in the dissemination of bla GES among
different bacterial genera and species from different environments around the world, and …

Guiana extended-spectrum (GES)-type enzymes are Ambler class A β-lactamases, and
some variants, such as GES-5, display carbapenemase activity [1]. Recent studies have …

Integrons are genetic platforms responsible for the dissemination of antimicrobial resistance
genes among Gram-negative bacteria, primarily due to their association with transposable …

Infections caused by metallo-beta-lactamase-producing organisms (MBLs) are a global
health threat. Our understanding of transmission dynamics and how MBLs establish …

Integrons are flexible gene-exchanging platforms that contain multiple cassettes encoding
accessory genes whose order is shuffled by a specific integrase. Integrons embedded within …

AmpC-type β-lactamases severely impair treatment of many bacterial infections, due to their
broad spectrum (they hydrolyze virtually all β-lactams, except fourth-generation …