Pathogenicity and virulence of human T lymphotropic virus type-1 (HTLV-1) in oncogenesis: adult T-cell leukemia/lymphoma (ATLL)

S Ahmadi Ghezeldasht, DJ Blackbourn… - Critical Reviews in …, 2023 - Taylor & Francis
Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy of CD4+ T
lymphocytes caused by human T lymphotropic virus type-1 (HTLV-1) infection. HTLV-1 was …

Understanding the Immunopathology of HTLV-1-Associated Adult T-Cell Leukemia/Lymphoma: A Comprehensive Review

S Nakahata, D Enriquez-Vera, MI Jahan, K Sugata… - Biomolecules, 2023 - mdpi.com
Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL).
HTLV-1 carriers have a lifelong asymptomatic balance between infected cells and host …

HTLV-1-host interactions on the development of adult T cell leukemia/lymphoma: virus and host gene expressions

H Tarokhian, H Rahimi, A Mosavat, A Shirdel… - BMC cancer, 2018 - Springer
Background Adult T-cell leukemia/lymphoma (ATLL) is a lymphoproliferative disorder of
HTLV-1-host interactions in infected TCD4+ cells. In this study, the HTLV-1 proviral load …

Molecular biology of human T cell leukemia virus

L Ratner - Seminars in diagnostic pathology, 2020 - Elsevier
Human T cell leukemia virus type 1 (HTLV-1) is a horizontally transmitted virus infection of
CD4+ lymphocytes which causes adult T cell leukemia-lymphoma (ATLL) and HTLV …

Human T-Cell Leukemia Virus Type 1 Oncogenesis between Active Expression and Latency: A Possible Source for the Development of Therapeutic Targets

F Marino-Merlo, S Grelli, A Mastino, M Lai… - International Journal of …, 2023 - mdpi.com
The human T-cell leukemia virus type 1 (HTLV-1) is the only known human oncogenic
retrovirus. HTLV-1 can cause a type of cancer called adult T-cell leukemia/lymphoma (ATL) …

Virological and immunological mechanisms in the pathogenesis of human T‐cell leukemia virus type 1

Y Satou, M Matsuoka - Reviews in medical virology, 2013 - Wiley Online Library
Human T‐cell leukemia virus type 1 (HTLV‐1) was the first retrovirus shown to cause human
disease, such as adult T‐cell leukemia and HTLV‐1 associated myelopathy/tropic spastic …

Current perspectives in human T-cell leukemia virus type 1 infection and its associated diseases

M Miura, T Naito, M Saito - Frontiers in Medicine, 2022 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) is a replication-competent human retrovirus
associated with two distinct types of diseases: a malignancy of mature CD4+ T cells called …

HTLV‐1 persistent infection and ATLL oncogenesis

X Zuo, R Zhou, S Yang, G Ma - Journal of Medical Virology, 2023 - Wiley Online Library
Human T‐cell leukemia virus type 1 (HTLV‐1) was discovered in the 1980s, but it is
estimated to have been infecting humans for more than ten thousand years. 1 With over 90 …

Human T-cell lymphotropic virus type 1 and its oncogenesis

L Zhang, J Wei, L Wang, S Huang… - Acta Pharmacologica …, 2017 - nature.com
Human T-cell lymphotropic virus type 1 (HTLV-1) is the etiologic agent of adult T-cell
leukemia/lymphoma (ATL), a rapidly progressing clonal malignancy of CD4+ T lymphocytes …

Strategies of human T-cell leukemia virus Type 1 for persistent infection: Implications for leukemogenesis of adult T-cell leukemia-lymphoma

J Yasunaga - Frontiers in microbiology, 2020 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) establishes persistent infection in vivo in two
distinct ways: de novo infection and clonal proliferation of infected cells. Two viral genes …