Pathways and genes involved in steroid hormone metabolism in male pigs: A review and update

A Robic, T Faraut, A Prunier - The Journal of steroid biochemistry and …, 2014 - Elsevier
This paper reviews state-of-the-art knowledge on steroid biosynthesis pathways in the pig
and provides an updated characterization of the porcine genes involved in these pathways …

Exploration of steroidogenesis‐related genes in testes, ovaries, adrenals, liver and adipose tissue in pigs

A Robic, K Feve, I Louveau, J Riquet… - Animal science …, 2016 - Wiley Online Library
To explore the metabolism of steroids in the pig species, a qualitative PCR analysis was
performed for the main transcript of 27 genes involved in steroid metabolism. We compared …

Ontogeny of expression and localization of steroidogenic enzymes in the neonatal and prepubertal pig testes

I Choi, JY Kim, EJ Lee, YY Kim, CS Chung… - Journal of …, 2009 - Wiley Online Library
The early neonatal development of boars is characterized by significant testicular production
of androgens and estrogens, including an anabolic steroid hormone, 19‐nortestosterone …

[HTML][HTML] Transcript profiling of candidate genes in testis of pigs exhibiting large differences in androstenone levels

E Grindflek, I Berget, M Moe, P Oeth, S Lien - BMC genetics, 2010 - Springer
Background Boar taint is an unpleasant odor and flavor of the meat and occurs in a high
proportion of uncastrated male pigs. Androstenone, a steroid produced in testis and acting …

Gene expression of 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase in relation to androstenone, testosterone, and estrone sulphate in …

G Chen, E Bourneuf, S Marklund… - Journal of animal …, 2007 - academic.oup.com
Androstenone is one of the main compounds responsible for boar taint, and 3β-
hydroxysteroid dehydrogenase (3βHSD) might be involved in its metabolism. In this study …

Effects of nuclear receptor transactivation on steroid hormone synthesis and gene expression in porcine Leydig cells

MA Gray, EJ Squires - The Journal of Steroid Biochemistry and Molecular …, 2013 - Elsevier
Male pigs are routinely castrated at a young age to prevent the formation of androstenone, a
16-androstene testicular steroid that is a major component of boar taint. The practice of …

Dexamethasone acutely down-regulates genes involved in steroidogenesis in stallion testes

NH Ing, DW Forrest, PK Riggs, S Loux, CC Love… - The Journal of steroid …, 2014 - Elsevier
In rodents, livestock and primate species, a single dose of the synthetic glucocorticoid
dexamethasone acutely lowers testosterone biosynthesis. To determine the mechanism of …

[PDF][PDF] Mammalian gonadal differentiation: the pig model

E Pailhoux, B Mandon-Pepin… - REPRODUCTION …, 2001 - biosciproceedings.org
In mammals, testicular differentiation is initiated by SRY (the sex-determining region of the Y
chromosome) gene expression in Sertoli cell precursors, followed by upregulation of the …

[HTML][HTML] Gene expression profiles in testis of pigs with extreme high and low levels of androstenone

M Moe, T Meuwissen, S Lien, C Bendixen, X Wang… - BMC genomics, 2007 - Springer
Background: Boar taint is a major obstacle when using uncastrated male pigs for swine
production. One of the main compounds causing this taint is androstenone, a pheromone …

Immunolocalization of steroidogenic enzymes P450scc, 3βHSD, P450c17, and P450arom in Göttingen miniature pig testes

Q Weng, MS Medan, G Watanabe… - … of Reproduction and …, 2005 - jstage.jst.go.jp
The objective of this study was to investigate immunolocalization of steroidogenic enzymes
in Göttingen miniature (GM) pig testes. Testes of 6 adult GM pigs were obtained in …