Ganciclovir is a nucleoside analogue of guanosine, a homologue of acyclovir, and the first
antiviral drug to be effective in the treatment of cytomegalovirus (CMV) disease in humans. 1 …

Synopsis The antiviral nucleoside analogue ganciclovir has demonstrated in vitro activity
against human cytomegalovirus and effectively treats infection caused by this organism in …

Synopsis Ganciclovir is a nucleoside analogue with antiviral activity in vitro against
members of the herpes group and some other DNA viruses. It has demonstrated efficacy …

Abstract Ganciclovir (9-[(1, 3-dihydroxy-2-propoxy) methyl] guanine) is a potent inhibitor of
viruses of the herpes family, including cytomegalovirus (CMV), that are pathogenic for …

Ganciclovir is a nucleoside analog which inhibits the replication of herpesviruses in vitro and
which has been effective by intravenous administration for the treatment of severe …

Ganciclovir is a congener of acyclovir with in vitro activity against cytomegalovirus. Ninety-
seven patients with the acquired immune deficiency syndrome (AIDS) and a serious …

Cytomegalovirus strains with reduced in vitro susceptibilities to ganciclovir have been
recovered from patients who failed long-term ganciclovir therapy. The ganciclovir-resistant …

Ganciclovir is a nucleoside guanosine analogue which incorporates ganciclovir
triphosphate (the active moiety) into DNA during elongation, thereby inhibiting viral …

The pharmacokinetics of ganciclovir was evaluated in 21 patients with life-or sight-
threatening cytomegalovirus infections. Thirteen patients had normal renal function and …

Valganciclovir (Valcyte™) is an orally administered prodrug of the standard anti-
cytomegalovirus (CMV) drug ganciclovir. Valganciclovir is as effective as intravenous …