Alzheimer's disease (AD) is characterized by memory impairment, neurochemically by
accumulation of β-amyloid peptide (namely Aβ1-42) and morphologically by an initial loss of …

Consumption of caffeine, an adenosine receptor antagonist, was found to be inversely
associated with the incidence of Alzheimer's disease. Moreover, caffeine protects cultured …

Alzheimer's disease (AD) is characterized by a progressive cognitive impairment tightly
correlated with the accumulation of amyloid-β (Aβ) peptides (mainly Aβ 1-42). There is a …

Adenosine A2A receptor antagonists alleviate memory deficits caused by aging or by
administration of β-amyloid peptides in rodents, which is in accordance with the beneficial …

Consumption of caffeine, a non-selective adenosine A2A receptor (A2AR) antagonist,
reduces the risk of developing Alzheimer's disease (AD) and mitigates both amyloid and Tau …

Adenosine is a neuromodulator in the nervous system and it has recently been observed
that pharmacological blockade or gene disruption of adenosine A2A receptors confers …

Caffeine, the most widely consumed psychoactive drug, enhances attention/vigilance,
stabilizes mood, and might also independently enhance cognitive performance. Notably …

Alzheimer's disease (AD) is a neurodegenerative disorder of the central nervous system
manifested by cognitive and memory deterioration, a variety of neuropsychiatric symptoms …

Consumption of caffeine, a non-selective adenosine A 2A receptor (A 2A R) antagonist,
reduces the risk of developing Alzheimer's disease (AD) in humans and mitigates both …

Abstract Adenosine A 2A receptors (A 2A R) overfunction causes synaptic and memory
dysfunction in early Alzheimer's disease (AD). In a β-amyloid (Aβ 1-42)-based model of early …