Biotin deficiency induces intestinal dysbiosis associated with an inflammatory bowel disease-like phenotype
Biotin is an essential vitamin and critical cofactor in several metabolic pathways, and its
deficiency has been linked to several disorders including inflammatory bowel disease (IBD) …
deficiency has been linked to several disorders including inflammatory bowel disease (IBD) …
Micronutrient deficiency in inflammatory bowel diseases: cause or effect?
D Jayawardena, PK Dudeja - Cellular and Molecular …, 2020 - cmghjournal.org
Inflammatory bowel diseases (IBDs), encompassing both Crohn's disease (CD) and
ulcerative colitis (UC), affect over 3 million individuals in the United States. 1 The …
ulcerative colitis (UC), affect over 3 million individuals in the United States. 1 The …
[HTML][HTML] Biotin supplementation ameliorates murine colitis by preventing NF-κB activation
J Skupsky, S Sabui, M Hwang, M Nakasaki… - Cellular and molecular …, 2020 - Elsevier
Background & Aims Biotin is a water-soluble vitamin that is indispensable for human health.
Biotin deficiency can cause failure-to-thrive, immunodeficiency, alopecia, dermatitis, and …
Biotin deficiency can cause failure-to-thrive, immunodeficiency, alopecia, dermatitis, and …
Relevance of biotin deficiency in patients with inflammatory bowel disease and utility of serum 3 hydroxyisovaleryl carnitine as a practical everyday marker
J Erbach, F Bonn, M Diesner, A Arnold, J Stein… - Journal of clinical …, 2022 - mdpi.com
Background: Biotin, a water-soluble B vitamin, has demonstrable anti-inflammatory
properties. A biotin-deficient diet induced a colitis-like phenotype in mice, alleviable by biotin …
properties. A biotin-deficient diet induced a colitis-like phenotype in mice, alleviable by biotin …
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism
Objectives Gut microbiota is a key component in obesity and type 2 diabetes, yet
mechanisms and metabolites central to this interaction remain unclear. We examined the …
mechanisms and metabolites central to this interaction remain unclear. We examined the …
[HTML][HTML] Biotin controls intestinal stem cell mitosis and host-microbiome interactions
C Neophytou, C Pitsouli - Cell Reports, 2022 - cell.com
Diet is a key regulator of metabolism and interacts with the intestinal microbiome. Here, we
study the role of the Drosophila intestinal stem cell (ISC)-specific biotin transporter Smvt in …
study the role of the Drosophila intestinal stem cell (ISC)-specific biotin transporter Smvt in …
Lipopolysaccharide inhibits colonic biotin uptake via interference with membrane expression of its transporter: a role for a casein kinase 2-mediated pathway
Biotin (vitamin B7), an essential micronutrient for normal cellular functions, is obtained from
both dietary sources as well as gut microbiota. Absorption of biotin in both the small and …
both dietary sources as well as gut microbiota. Absorption of biotin in both the small and …
Vitamin B12 deficiency alters the gut microbiota in a murine model of colitis
Purpose: Inflammatory bowel disease (IBD) refers to a spectrum of autoimmune diseases,
which result in chronic intestinal inflammation. Previous findings suggest a role for diet …
which result in chronic intestinal inflammation. Previous findings suggest a role for diet …
Probiotic Bifidobacterium longum alters gut luminal metabolism through modification of the gut microbial community
H Sugahara, T Odamaki, S Fukuda, T Kato, J Xiao… - Scientific reports, 2015 - nature.com
Probiotics are well known as health-promoting agents that modulate intestinal microbiota.
However, the molecular mechanisms underlying this effect remain unclear. Using …
However, the molecular mechanisms underlying this effect remain unclear. Using …
B-vitamin deficiency is protective against DSS-induced colitis in mice
NM Benight, B Stoll, S Chacko… - American Journal …, 2011 - journals.physiology.org
Vitamin deficiencies are common in patients with inflammatory bowel disease (IBD).
Homocysteine (Hcys) is a thrombogenic amino acid produced from methionine (Met), and its …
Homocysteine (Hcys) is a thrombogenic amino acid produced from methionine (Met), and its …