Antibiotics-free nanoparticles eradicate Helicobacter pylori biofilms and intracellular bacteria

Y Zou, X Chen, Y Sun, P Li, M Xu, P Fang… - Journal of Controlled …, 2022 - Elsevier
Biofilms and intracellular survival tremendously help Helicobacter pylori (H. pylori) escape
from antibacterial agents attacking, therefore issuing extreme challenges to clinical …

Future Nanotechnology‐Based Strategies for Improved Management of Helicobacter pylori Infection

M Kamankesh, A Yadegar, A Llopis‐Lorente, C Liu… - Small, 2024 - Wiley Online Library
Helicobacter pylori (H. pylori) is a recalcitrant pathogen, which can cause gastric disorders.
During the past decades, polypharmacy‐based regimens, such as triple and quadruple …

Coating Nanoparticles with Gastric Epithelial Cell Membrane for Targeted Antibiotic Delivery against Helicobacter pylori Infection

P Angsantikul, S Thamphiwatana, Q Zhang… - Advanced …, 2018 - Wiley Online Library
Inspired by the natural pathogen–host interactions and adhesion, this study reports on the
development of a novel targeted nanotherapeutic for the treatment of Helicobacter pylori …

Biomaterials for Helicobacter pylori therapy: therapeutic potential and future perspectives

Y Lai, W Wei, Y Du, J Gao, Z Li - Gut Microbes, 2022 - Taylor & Francis
Helicobacter pylori (H. pylori) is the main cause of gastric adenocarcinoma. However, the
traditional antibiotic treatment of H. pylori is limited due to increased antibiotic resistance …

Genipin-cross-linked fucose–chitosan/heparin nanoparticles for the eradication of Helicobacter pylori

YH Lin, SC Tsai, CH Lai, CH Lee, ZS He, GC Tseng - Biomaterials, 2013 - Elsevier
Helicobacter pylori is a significant human pathogen that recognizes specific carbohydrate
receptors, such as the fucose receptor, and produces the vacuolating cytotoxin, which …

Engineering bioinspired bacteria-adhesive clay nanoparticles with a membrane-disruptive property for the treatment of Helicobacter pylori infection

Y Ping, X Hu, Q Yao, Q Hu, S Amini, A Miserez, G Tang - Nanoscale, 2016 - pubs.rsc.org
We present a bioinspired design strategy to engineer bacteria-targeting and membrane-
disruptive nanoparticles for the effective antibiotic therapy of Helicobacter pylori (H. pylori) …

Berberine-Loaded Targeted Nanoparticles as Specific Helicobacter Pylori Eradication Therapy: In Vitro and In Vivo Study

YH Lin, JH Lin, SC Chou, SJ Chang, CC Chung… - …, 2015 - Taylor & Francis
Aim: The aim of this work was to develop fucose-conjugated nanoparticles and control the
release of berberine, and demonstrate that these particles come into contact with …

Mucus penetration enhanced lipid polymer nanoparticles improve the eradication rate of Helicobacter pylori biofilm

P Li, X Chen, Y Shen, H Li, Y Zou, G Yuan, P Hu… - Journal of Controlled …, 2019 - Elsevier
The resistance of Helicobacter pylori (H. pylori) to conventional antibiotic treatments
becomes prevalent recently. The biofilm formation was found to be highly correlated with the …

Development of genipin-crosslinked fucoidan/chitosan-N-arginine nanogels for preventing Helicobacter infection

YH Lin, KY Lu, CL Tseng, JY Wu, CH Chen, FL Mi - Nanomedicine, 2017 - Taylor & Francis
Aim: This study aims to validate the anti-Helicobacter pylori efficacy of amoxicillin-loaded
nanoparticles and nanogels with pH-responsive and site-specific drug release properties …

Combatting Helicobacter pylori with oral nanomedicines

Y Qin, YH Lao, H Wang, J Zhang, K Yi… - Journal of Materials …, 2021 - pubs.rsc.org
Helicobacter pylori (H. pylori) infection is considered to be the main cause of most digestive
diseases, such as chronic active gastritis, gastroduodenal ulcers, or even gastric cancer …