Structurally simplified analogues of ansellone A, in which the decalin skeleton is replaced
with a lipophilic chain, were prepared and their HIV latency‐reversing activities biologically …

The total synthesis and biological evaluation of the marine sesterterpenoid ansellone A (1),
an HIV latency-reversing agent, and its analogues are reported. The key to the success of …

Three new diterpenes, stellejasmins A (1) and B (2) and 12-O-benzoylphorbol-13-
heptanoate (3), were isolated from the roots of Stellera chamaejasme L. The structures of 1 …

Five new minor sesterterpenoids, ansellones H (4), I (5), J (6), and K (7) and phorone C (8),
have been isolated from a Phorbas sp. marine sponge collected in British Columbia. Their …

The first total synthesis of marine sesterterpenoid ansellone G (2) was accomplished. This
strategy utilizes the Prins cyclization reaction of a chloro-substituted homoallyl alcohol to …

Screening of a marine natural products library afforded three new analogues of the tetronic
acid containing polyketide abyssomicin family and identified abyssomicin 2 as a selective …

Cells latently infected with human immunodeficiency virus type 1 (HIV-1) prevent people
living with HIV-1 from obtaining a cure to the infectious disease. Latency reversing agents …

Forty-two dihydroseselins based on the structure of suksdorfin (1) were synthesized in order
to evaluate their anti-HIV activity. These synthetic derivatives include 3', 4'-di-0-acyl-and 3'-or …

Tigliane diterpenoids possess exceptionally complex structures comprising common 5/7/6/3-
membered ABCD-rings and disparate oxygen functionalities. While tiglianes display a wide …

Inhibitors of glycoprotein processing, such as castanospermine (1, 6, 7, 8-
tetrahydroxyoctahydroindolizine), have been shown previously to inhibit human …