Organ transplantation often depends on obtaining functioning organs from a donor who has
recently died. This review presents a structured approach to management of the care of the …

Caring for a brain dead potential organ donor requires a shift in critical care from the
extensive treatment of increased intracranial pressure towards strategies to maintain donor …

Brain death is associated with complex hemodynamic, endocrine, and metabolic dysfunction
that can lead to major complications with the potential donor. Untreated, this can progress to …

The systemic physiologic changes that occur during and after brain death affect all organs
suitable for transplantation. Major changes occur in the cardiovascular, pulmonary …

With improving healthcare services, the demand for organ transplants has been increasing
daily worldwide. Deceased organ donors serve as a good alternative option to meet this …

Brain death has specific implications for organ donation with the potential for saving several
lives. Awareness on maintenance of the brain dead has increased over the last decade with …

The widespread physiologic changes that follow brain stem death lead to a high incidence
of complications in the donor and jeopardize vital organ function. Strategies for the …

Abstract Experiments in Cape Town in the 1980s demonstrated that acute brain death is
followed by massive catecholamine release resulting in systemic hypertension, acute left …

Background. Brain death results in adverse pathophysiologic effects in many cadaveric
donors, resulting in cardiovascular instability and poor organ perfusion. Hormonal …

In recent years, transplantation has assumed an important role in the treatment of patients
with end-stage diseases of most major organ systems. However, the greatest limitation in …