Radiation combined with immune checkpoint inhibitors for unresectable locally advanced non-small cell lung cancer: synergistic mechanisms, current state …
L Wu, Z Zhang, M Bai, Y Yan, J Yu, Y Xu - Cell Communication and …, 2023 - Springer
Until the advent of immune checkpoint inhibitors (ICIs), definitive radiotherapy (RT)
concurrently with chemotherapy was recommended for unresectable, locally advanced non …
concurrently with chemotherapy was recommended for unresectable, locally advanced non …
[HTML][HTML] Radiotherapy for non-small cell lung cancer in the immunotherapy era: the opportunity and challenge—a narrative review
WY Xia, W Feng, CC Zhang, YJ Shen… - Translational Lung …, 2020 - ncbi.nlm.nih.gov
Immunotherapy has radically changed the clinical management of patients with cancer in
recent years. Immune checkpoint inhibitors (ICIs) reversing the immunosuppressive effects …
recent years. Immune checkpoint inhibitors (ICIs) reversing the immunosuppressive effects …
Synergistic effect of immunotherapy and radiotherapy in non-small cell lung cancer: current clinical trials and prospective challenges
H Yang, T Jin, M Li, J Xue, B Lu - Precision Clinical Medicine, 2019 - academic.oup.com
Lately, the success of ICIs has drastically changed the landscape of cancer treatment, and
several immune checkpoint inhibitors (ICIs) have been approved by the US Food and Drug …
several immune checkpoint inhibitors (ICIs) have been approved by the US Food and Drug …
[HTML][HTML] Is the combination of immunotherapy and radiotherapy in non-small cell lung cancer a feasible and effective approach?
M Spaas, Y Lievens - Frontiers in medicine, 2019 - frontiersin.org
For many years, conventional oncologic treatments such as surgery, chemotherapy, and
radiotherapy (RT) have dominated the field of non-small-cell lung cancer (NSCLC). The …
radiotherapy (RT) have dominated the field of non-small-cell lung cancer (NSCLC). The …
Chemoradioimmunotherapy of inoperable stage III non-small cell lung cancer: immunological rationale and current clinical trials establishing a novel multimodal …
L Käsmann, C Eze, J Taugner, O Roengvoraphoj… - Radiation …, 2020 - Springer
Immune-checkpoint inhibitors (ICI) have dramatically changed the landscape of lung cancer
treatment. Preclinical studies investigating combination of ICI with radiation show a …
treatment. Preclinical studies investigating combination of ICI with radiation show a …
Safety and efficacy of radiotherapy/chemoradiotherapy combined with immune checkpoint inhibitors for non-small cell lung cancer: A systematic review and meta …
J Wu, T Ni, R Deng, Y Li, Q Zhong, F Tang… - Frontiers in …, 2023 - frontiersin.org
Background It is now widely accepted that radiotherapy (RT) can provoke a systemic
immune response, which gives a strong rationale for the combination of RT and immune …
immune response, which gives a strong rationale for the combination of RT and immune …
Induction immune checkpoint inhibitors and chemotherapy before definitive chemoradiation therapy for patients with bulky unresectable stage III non-small cell lung …
Y Wang, T Zhang, J Wang, Z Zhou, W Liu, Z Xiao… - International Journal of …, 2023 - Elsevier
Purpose In the era of immunotherapy, the treatment for bulky, locally advanced non-small
cell lung cancer (LA-NSCLC) remains challenging. This study explored the feasibility of …
cell lung cancer (LA-NSCLC) remains challenging. This study explored the feasibility of …
[HTML][HTML] Radiation and immunotherapy combinations in non-small cell lung cancer
S Azghadi, ME Daly - Cancer Treatment and Research Communications, 2021 - Elsevier
Non-small cell lung cancer (NSCLC) is a common and lethal malignancy. The recent
development of immune checkpoint inhibitors has afforded a durable, dramatic treatment …
development of immune checkpoint inhibitors has afforded a durable, dramatic treatment …
Immunoradiotherapy as an effective therapeutic strategy in lung cancer: From palliative care to curative intent
R Chicas-Sett, J Zafra-Martin, I Morales-Orue… - Cancers, 2020 - mdpi.com
Lung cancer is one of the main causes of cancer-related mortality worldwide. Over the years,
different therapeutic modalities have been adopted depending on tumor stage and patient …
different therapeutic modalities have been adopted depending on tumor stage and patient …
Beyond concurrent chemoradiation: the emerging role of PD-1/PD-L1 inhibitors in stage III lung cancer
Concurrent chemoradiation (cCRT) with platinum-based chemotherapy is standard-of-care
therapy for patients with stage III unresectable non–small cell lung cancer (NSCLC) …
therapy for patients with stage III unresectable non–small cell lung cancer (NSCLC) …
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