Efficacy and toxicity of decitabine versus CHG regimen (low-dose cytarabine, homoharringtonine and granulocyte colony-stimulating factor) in patients with higher risk …
L Wu, X Li, C Chang, F Xu, Q He, D Wu… - Leukemia & …, 2016 - Taylor & Francis
Decitabine and CHG regimen (low-dose cytarabine and homoharringtonine with G-CSF)
have been used for treating higher risk myelodysplastic syndrome (MDS). In this study, we …
have been used for treating higher risk myelodysplastic syndrome (MDS). In this study, we …
Update of the decitabine experience in higher risk myelodysplastic syndrome and analysis of prognostic factors associated with outcome
HM Kantarjian, S O'Brien, J Shan, A Aribi… - Cancer, 2007 - Wiley Online Library
BACKGROUND. Therapy for patients with myelodysplastic syndrome (MDS) with
hypomethylating agents, like decitabine and 5‐azacitidine, has produced favorable results …
hypomethylating agents, like decitabine and 5‐azacitidine, has produced favorable results …
Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome: comparison with historical experience
HM Kantarjian, S O'Brien, X Huang… - … Journal of the …, 2007 - Wiley Online Library
BACKGROUND Decitabine, a hypomethylating agent, is active and has been approved for
the treatment of myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia …
the treatment of myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia …
Decitabine for myelodysplastic syndromes: dose comparison in a real world clinical setting
Y Ren, H Jiang, F Shi, L Ye, Y Luo, X Zhou… - Leukemia & …, 2019 - Taylor & Francis
We retrospectively studied 133 myelodysplastic syndrome patients receiving decitabine
during January 2009 and September 2017. The dose of 15 mg/m 2/d (n= 83) and 20 mg/m …
during January 2009 and September 2017. The dose of 15 mg/m 2/d (n= 83) and 20 mg/m …
Decitabine of reduced dosage in Chinese patients with myelodysplastic syndrome: a retrospective analysis
X Li, Q Song, Y Chen, C Chang, D Wu, L Wu, J Su… - PloS one, 2014 - journals.plos.org
Decitabine has been approved for the treatment of all subtypes of myelodysplastic syndrome
(MDS). However, the optimal regimen for decitabine treatment is not well established. In this …
(MDS). However, the optimal regimen for decitabine treatment is not well established. In this …
Very-low-dose decitabine is effective in treating intermediate-or high-risk myelodysplastic syndrome
H Li, L Wang, Y Wu, L Su, H Zhao, Y Zhang… - Acta …, 2017 - karger.com
Nowadays, the regular recommended dose of decitabine for the treatment of
myelodysplastic syndrome (MDS) is 20 mg/m2/day for 5 consecutive days with a relatively …
myelodysplastic syndrome (MDS) is 20 mg/m2/day for 5 consecutive days with a relatively …
Randomized open-label phase II study of decitabine in patients with low-or intermediate-risk myelodysplastic syndromes
G Garcia-Manero, E Jabbour, G Borthakur… - Journal of clinical …, 2013 - ascopubs.org
Purpose This open-label, randomized phase II trial assessed efficacy and tolerability of two
low-dose regimens of subcutaneous (SC) decitabine in patients with low-or intermediate-1 …
low-dose regimens of subcutaneous (SC) decitabine in patients with low-or intermediate-1 …
Phase I/II study of decitabine in patients with myelodysplastic syndrome: A multi‐center study in J apan
Y Oki, Y Kondo, K Yamamoto, M Ogura… - Cancer …, 2012 - Wiley Online Library
The management of myelodysplastic syndrome (MDS) remains challenging. We performed
a phase I/II study to evaluate the safety and efficacy of decitabine in patients with MDS in …
a phase I/II study to evaluate the safety and efficacy of decitabine in patients with MDS in …
Comparison of clinical efficacy between decitabine combined with CAG regimen and CAG regimen alone in patients with intermediate to high-risk myelodysplastic …
YP Zhang, WZ Wu, GX Cui - Zhongguo shi yan xue ye xue za zhi, 2014 - europepmc.org
This study was purposed to compare the clinical efficacy and adverse reactions of low-dose
decitabine combined with CAG regimen (aclarubicin, Ara-C, and G-CSF) and CAG regimen …
decitabine combined with CAG regimen (aclarubicin, Ara-C, and G-CSF) and CAG regimen …
Decitabine Low-Dose Schedule (100 mg/m2/course) in Myelodysplastic Syndrome (MDS). Comparison of 3 Different Dose Schedules.
HM Kantarjian, F Ravandi, S O'Brien, F Giles, S Faderl… - Blood, 2004 - Elsevier
Decitabine, a hypomethylating agent, has shown activity in MDS, acute myeloid leukemia
(AML), and chronic myeloid leukemia. In this study, we investigated optimizing the dose …
(AML), and chronic myeloid leukemia. In this study, we investigated optimizing the dose …
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