Coupling magnetic levitation of graphene oxide–protein complexes with blood levels of glucose for early detection of pancreatic adenocarcinoma

E Quagliarini, D Caputo, R Cammarata… - Cancer …, 2023 - Springer
Introduction Pancreatic adenocarcinoma (PDAC) has a poor prognosis since often
diagnosed too late. Dyslipidemia and hyperglycemia are considered risk factors, but the …

Detection of pancreatic ductal adenocarcinoma by ex vivo magnetic levitation of plasma protein-coated nanoparticles

L Digiacomo, E Quagliarini, V La Vaccara, A Coppola… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic Ductal Adeno Carcinoma (PDAC) is a highly lethal disease, for
which mortality closely parallels incidence. The poor prognosis of PDAC is mainly due to …

Inflammatory biomarkers and nanotechnology: new insights in pancreatic cancer early detection

D Caputo, E Quagliarini, A Coppola… - … Journal of Surgery, 2023 - journals.lww.com
Background: Poor prognosis of pancreatic ductal adenocarcinoma (PDAC) is mainly due to
the lack of effective early-stage detection strategies. Even though the link between …

Synergistic analysis of protein corona and haemoglobin levels detects pancreatic cancer

D Caputo, L Digiacomo, C Cascone, D Pozzi… - Cancers, 2020 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is often diagnosed at an
advanced stage and is burdened by poor prognosis. Its early diagnosis is rare because the …

Magnetic levitation patterns of microfluidic-generated nanoparticle–protein complexes

L Digiacomo, E Quagliarini, B Marmiroli, B Sartori… - Nanomaterials, 2022 - mdpi.com
Magnetic levitation (MagLev) has recently emerged as a powerful method to develop
diagnostic technologies based on the exploitation of the nanoparticle (NP)–protein corona …

Magnetic levitation of personalized nanoparticle–protein corona as an effective tool for cancer detection

E Quagliarini, L Digiacomo, D Caputo, A Coppola… - Nanomaterials, 2022 - mdpi.com
Unprecedented opportunities for early stage cancer detection have recently emerged from
the characterization of the personalized protein corona (PC), ie, the protein cloud that …

A reusable magnetic graphene oxide-modified biosensor for vascular endothelial growth factor detection in cancer diagnosis

CW Lin, KC Wei, S Liao, CY Huang, CL Sun… - Biosensors and …, 2015 - Elsevier
Early cancer diagnosis is critical for the prevention of metastasis. However, simple and
efficient methods are needed to improve the diagnosis and evaluation of cancer. Here, we …

Personalized graphene oxide-protein corona in the human plasma of pancreatic cancer patients

R Di Santo, L Digiacomo, E Quagliarini… - … in bioengineering and …, 2020 - frontiersin.org
The protein corona (PC) that forms around nanomaterials upon exposure to human biofluids
(eg, serum, plasma, cerebral spinal fluid etc.) is personalized, ie, it depends on alterations of …

Graphene sensor arrays for rapid and accurate detection of pancreatic cancer exosomes in patients' blood plasma samples

T Yin, L Xu, B Gil, N Merali, MS Sokolikova… - ACS …, 2023 - ACS Publications
Biosensors based on graphene field effect transistors (GFETs) have the potential to enable
the development of point-of-care diagnostic tools for early stage disease detection …

Multifunctional nanoparticles for protein detections in thin channels

H Tsai, W Lin, M Chuang, Y Lu, CB Fuh - Biosensors and Bioelectronics, 2017 - Elsevier
This paper presents a method for simultaneous detection of two proteins by using
multifunctional nanoparticles with a magnetic immunoassay in thin channels. Biofunctional …