[HTML][HTML] The interaction between reactive peritoneal mesothelial cells and tumor cells via extracellular vesicles facilitates colorectal cancer dissemination

S Serratì, L Porcelli, F Fragassi, M Garofoli, R Di Fonte… - Cancers, 2021 - mdpi.com
Simple Summary Emerging evidence has suggested that cancer-derived extracellular
vesicles (EVs) have a crucial role in mediating directional metastasis to the peritoneal …

[HTML][HTML] Extracellular vesicles shed from gastric cancer mediate protumor macrophage differentiation

A Ito, S Kagawa, S Sakamoto, K Kuwada, H Kajioka… - BMC cancer, 2021 - Springer
Background Peritoneal dissemination often develops in gastric cancer. Tumor-associated
macrophages (TAMs) are present in the peritoneal cavity of gastric cancer patients with …

[HTML][HTML] The role of extracellular vesicles as modulators of the tumor microenvironment, metastasis and drug resistance in colorectal cancer

KS Siveen, A Raza, EI Ahmed, AQ Khan, KS Prabhu… - Cancers, 2019 - mdpi.com
Colorectal cancer (CRC) is one of the most common cancers worldwide, with high morbidity
and mortality rates. A number of factors including modulation of the tumor microenvironment …

[HTML][HTML] The biological effect of small extracellular vesicles on colorectal cancer metastasis

X Wang, D Huang, J Wu, Z Li, X Yi, T Zhong - Cells, 2022 - mdpi.com
Colorectal cancer (CRC) is a malignancy that seriously threatens human health, and
metastasis from CRC is a major cause of death and poor prognosis for patients. Studying the …

Cancer cell-derived extracellular vesicles activate hepatic stellate cells in colorectal cancer

BY Patel, R Bhome, DSK Liu, E Giovannetti… - Expert review of …, 2023 - Taylor & Francis
Colorectal cancer (CRC) is the 2nd leading cause of cancer-related deaths worldwide,
primarily due to the development of metastatic disease. The liver is the most frequently …

Small extracellular vesicles promote the formation of the pre-metastatic niche through multiple mechanisms in colorectal cancer

J Wu, X Wang, Z Li, X Yi, D Hu, Q Wang, T Zhong - Cell Cycle, 2024 - Taylor & Francis
Colorectal cancer (CRC) ranks among the most prevalent global malignancies, posing
significant threats to human life and health due to its high recurrence and metastatic …

[HTML][HTML] Small extracellular vesicles: key forces mediating the development and metastasis of colorectal cancer

W Zhang, X Hu, Z Jiang - Cells, 2022 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer worldwide, and its incidence and
mortality rates have been increasing annually in recent years. A variety of different small …

[HTML][HTML] The multifaceted role of extracellular vesicles (EVs) in colorectal cancer: metastasis, immune suppression, therapy resistance, and autophagy crosstalk

S Rahmati, A Moeinafshar, N Rezaei - Journal of Translational Medicine, 2024 - Springer
Extracellular vesicles (EVs) are lipid bilayer structures released by all cells and widely
distributed in all biological fluids. EVs are implicated in diverse physiopathological …

Gastric cancer‐derived exosomes promote peritoneal metastasis by destroying the mesothelial barrier

G Deng, J Qu, Y Zhang, X Che, Y Cheng, Y Fan… - Febs …, 2017 - Wiley Online Library
An intact mesothelium serves as a protective barrier to inhibit peritoneal carcinomatosis.
Cancer‐derived exosomes can mediate directional tumor metastasis; however, little is …

[HTML][HTML] Tumor exosome-mediated promotion of adhesion to mesothelial cells in gastric cancer cells

T Arita, D Ichikawa, H Konishi, S Komatsu, A Shiozaki… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Background Peritoneal metastasis consists of a highly complex series of steps, and the
details of the underlying molecular mechanism remain largely unclear. In this study, the …