New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs

A Müllertz, A Ogbonna, S Ren… - Journal of pharmacy and …, 2010 - academic.oup.com
Objectives The aim of this review is to highlight relevant considerations when implementing
a rational strategy for the development of lipid and surfactant based drug delivery system …

Lipid excipients and delivery systems for pharmaceutical development: a regulatory perspective

ML Chen - Advanced drug delivery reviews, 2008 - Elsevier
The use of lipid-based dosage forms for enhancement of drug absorption or delivery has
drawn considerable interest from pharmaceutical scientists. The unique characteristics of …

Lipid-based formulations for oral administration of poorly water-soluble drugs

H Mu, R Holm, A Müllertz - International journal of pharmaceutics, 2013 - Elsevier
Lipid-based drug delivery systems have shown great potentials in oral delivery of poorly
water-soluble drugs, primarily for lipophilic drugs, with several successfully marketed …

Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies

CW Pouton, CJH Porter - Advanced drug delivery reviews, 2008 - Elsevier
Oral lipid-based drug delivery systems may include a broad range of oils, surfactants, and
cosolvents. This diversity makes comparison of lipid-based formulations difficult. Although …

Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs

BK Nanjwade, DJ Patel, RA Udhani, FV Manvi - Scientia pharmaceutica, 2011 - mdpi.com
Lipid-based formulations encompass a diverse group of formulations with very different
physical appearance, ranging from simple triglyceride vehicles to more sophisticated …

Fundamental aspects of lipid-based excipients in lipid-based product development

D Nakmode, V Bhavana, P Thakor, J Madan, PK Singh… - Pharmaceutics, 2022 - mdpi.com
Poor aqueous solubility of drugs is still a foremost challenge in pharmaceutical product
development. The use of lipids in designing formulations provides an opportunity to …

Lipid-based formulations for oral delivery of lipophilic drugs

M Kuentz - Drug Discovery Today: Technologies, 2012 - Elsevier
In the last decade there has been a growing interest in lipid-based formulations to deliver
challenging compounds such as lipophilic drugs. Following a brief clarification of the …

Oral lipid-based formulations

DJ Hauss - Advanced drug delivery reviews, 2007 - Elsevier
Poor drug solubility remains a significant and frequently encountered problem for
pharmaceutical scientists. The ability of lipid-based formulations to facilitate gastrointestinal …

Enhancing intestinal drug solubilisation using lipid-based delivery systems

CJH Porter, CW Pouton, JF Cuine… - Advanced drug delivery …, 2008 - Elsevier
Lipid-based delivery systems are finding increasing application in the oral delivery of poorly
water-soluble, lipophilic drugs. Whilst lipidic dose forms may improve oral bioavailability via …

Lipid–an emerging platform for oral delivery of drugs with poor bioavailability

S Chakraborty, D Shukla, B Mishra, S Singh - European journal of …, 2009 - Elsevier
The sole objective of pharmaceutical science is to design successful dosage forms which
fulfill the therapeutic needs of the patients effectively. Development of new drug entities is …