New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs
A Müllertz, A Ogbonna, S Ren… - Journal of pharmacy and …, 2010 - academic.oup.com
Objectives The aim of this review is to highlight relevant considerations when implementing
a rational strategy for the development of lipid and surfactant based drug delivery system …
a rational strategy for the development of lipid and surfactant based drug delivery system …
Lipid excipients and delivery systems for pharmaceutical development: a regulatory perspective
ML Chen - Advanced drug delivery reviews, 2008 - Elsevier
The use of lipid-based dosage forms for enhancement of drug absorption or delivery has
drawn considerable interest from pharmaceutical scientists. The unique characteristics of …
drawn considerable interest from pharmaceutical scientists. The unique characteristics of …
Lipid-based formulations for oral administration of poorly water-soluble drugs
Lipid-based drug delivery systems have shown great potentials in oral delivery of poorly
water-soluble drugs, primarily for lipophilic drugs, with several successfully marketed …
water-soluble drugs, primarily for lipophilic drugs, with several successfully marketed …
Formulation of lipid-based delivery systems for oral administration: materials, methods and strategies
CW Pouton, CJH Porter - Advanced drug delivery reviews, 2008 - Elsevier
Oral lipid-based drug delivery systems may include a broad range of oils, surfactants, and
cosolvents. This diversity makes comparison of lipid-based formulations difficult. Although …
cosolvents. This diversity makes comparison of lipid-based formulations difficult. Although …
Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs
BK Nanjwade, DJ Patel, RA Udhani, FV Manvi - Scientia pharmaceutica, 2011 - mdpi.com
Lipid-based formulations encompass a diverse group of formulations with very different
physical appearance, ranging from simple triglyceride vehicles to more sophisticated …
physical appearance, ranging from simple triglyceride vehicles to more sophisticated …
Fundamental aspects of lipid-based excipients in lipid-based product development
Poor aqueous solubility of drugs is still a foremost challenge in pharmaceutical product
development. The use of lipids in designing formulations provides an opportunity to …
development. The use of lipids in designing formulations provides an opportunity to …
Lipid-based formulations for oral delivery of lipophilic drugs
M Kuentz - Drug Discovery Today: Technologies, 2012 - Elsevier
In the last decade there has been a growing interest in lipid-based formulations to deliver
challenging compounds such as lipophilic drugs. Following a brief clarification of the …
challenging compounds such as lipophilic drugs. Following a brief clarification of the …
Oral lipid-based formulations
DJ Hauss - Advanced drug delivery reviews, 2007 - Elsevier
Poor drug solubility remains a significant and frequently encountered problem for
pharmaceutical scientists. The ability of lipid-based formulations to facilitate gastrointestinal …
pharmaceutical scientists. The ability of lipid-based formulations to facilitate gastrointestinal …
Enhancing intestinal drug solubilisation using lipid-based delivery systems
CJH Porter, CW Pouton, JF Cuine… - Advanced drug delivery …, 2008 - Elsevier
Lipid-based delivery systems are finding increasing application in the oral delivery of poorly
water-soluble, lipophilic drugs. Whilst lipidic dose forms may improve oral bioavailability via …
water-soluble, lipophilic drugs. Whilst lipidic dose forms may improve oral bioavailability via …
Lipid–an emerging platform for oral delivery of drugs with poor bioavailability
The sole objective of pharmaceutical science is to design successful dosage forms which
fulfill the therapeutic needs of the patients effectively. Development of new drug entities is …
fulfill the therapeutic needs of the patients effectively. Development of new drug entities is …