Network pharmacology prediction and molecular docking-based strategy to explore the potential mechanism of Huanglian Jiedu Decoction against sepsis

X Li, S Wei, S Niu, X Ma, H Li, M Jing, Y Zhao - Computers in biology and …, 2022 - Elsevier
Abstract Background Huanglian Jiedu Decoction (HLJDD) is a classical herbal formula with
potential efficacy in the treatment of sepsis. However, the main components and potential …

[HTML][HTML] Network pharmacology to explore the anti-inflammatory mechanism of Xuebijing in the treatment of sepsis

W Zhou, X Lai, X Wang, X Yao, W Wang, S Li - Phytomedicine, 2021 - Elsevier
Background Xuebijing (XBJ) is a traditional Chinese patent medicine for sepsis. However,
the mechanism of action (MoA) of XBJ on sepsis remain unclear. Purpose Elucidate the MoA …

[HTML][HTML] Decoding the mechanism of huanglian jiedu decoction in treating pneumonia based on network pharmacology and molecular docking

X Li, H Tang, Q Tang, W Chen - Frontiers in cell and developmental …, 2021 - frontiersin.org
Huang-Lian-Jie-Du decoction (HLJDD) has been used to treat pneumonia for thousands of
years in China. However, our understanding of its mechanisms on treating pneumonia is still …

Molecular mechanism of the effect of Huanglian Jiedu decoction on type 2 diabetes mellitus based on network pharmacology and molecular docking

B Yin, YM Bi, GJ Fan, YQ Xia - Journal of Diabetes Research, 2020 - Wiley Online Library
Background. Huanglian Jiedu Decoction (HLJDD) is a Traditional Chinese Medicine (TCM)
formula comprising four herbal medicines. This decoction has long been used in China for …

[HTML][HTML] Mechanism of Dayuanyin in the treatment of coronavirus disease 2019 based on network pharmacology and molecular docking

X Ruan, P Du, K Zhao, J Huang, H Xia, D Dai… - Chinese Medicine, 2020 - Springer
Background At present, coronavirus disease 2019 (COVID-19), caused by infection with
severe acute respiratory syndrome coronavirus 2, is spreading all over the world, with …

Exploration of the mechanism of Zisheng Shenqi decoction against gout arthritis using network pharmacology

WH Li, JR Han, PP Ren, Y Xie, DY Jiang - Computational biology and …, 2021 - Elsevier
Background In this study, the network pharmacological methods were used to predict the
target of effective components of compounds in Zisheng Shenqi Decoction (ZSD, or …

Systems pharmacological study illustrates the immune regulation, anti-infection, anti-inflammation, and multi-organ protection mechanism of Qing-Fei-Pai-Du …

J Zhao, S Tian, D Lu, J Yang, H Zeng, F Zhang, D Tu… - Phytomedicine, 2021 - Elsevier
Abstract Background The traditional Chinese medicine (TCM) formula Qing-Fei-Pai-Du
decoction (QFPDD) was the most widely used prescription in China's campaign to contain …

[HTML][HTML] Integrated bioinformatics and network pharmacology to identify the therapeutic target and molecular mechanisms of Huangqin decoction on ulcerative Colitis

Y Wu, X Liu, G Li - Scientific reports, 2022 - nature.com
Huangqin decoction (HQD) is a Traditional Chinese Medicine formula for ulcerative colitis.
However, the pharmacology and molecular mechanism of HQD on ulcerative colitis is still …

[HTML][HTML] Mechanisms underlying the therapeutic effects of Qingfeiyin in treating acute lung injury based on GEO datasets, network pharmacology and molecular …

Y Wang, Y Yuan, W Wang, Y He, H Zhong… - Computers in biology …, 2022 - Elsevier
Background Qingfeiyin (QFY) is a common Chinese herbal formula for the treatment of acute
lung injury (ALI). However, its mechanisms of action are unclear. In this study, we …

Exploring material basis and mechanism of Lianhua Qingwen prescription against coronavirus based on network pharmacology

XY Ling - Chinese Traditional and Herbal Drugs, 2020 - pesquisa.bvsalud.org
Objective: To explore the active compounds and mechanism of Lianhua Qingwen
Prescription for the treatment of coronavirus, and provide a reference for the treatment of …