Investigating the complexity of host-pathogen interactions is challenging. Here, we outline a
pipeline to identify important proteins and signaling molecules in human-viral interactomes …

While knowledge of protein-protein interactions (PPIs) is critical for understanding virus-host
relationships, limitations on the scalability of high-throughput methods have hampered their …

Infectious diseases caused by viral agents kill millions of people every year. The
improvement of prevention and treatment of viral infections and their associated diseases …

Infections with human herpesviruses are ubiquitous and a public health concern worldwide.
Current treatments reduce the severity of some symptoms associated to herpetic infections …

The protein-protein interactions (PPIs) between human and viruses play important roles in
viral infection and host immune responses. Rapid accumulation of experimentally validated …

Computational analysis of human-virus protein-protein interaction (PPI) data is an effective
way toward systems understanding the molecular mechanism of viral infection. Previous …

Viral infections result in millions of deaths in the world today. A thorough analysis of virus‐
host interactomes may reveal insights into viral infection and pathogenic strategies. In this …

Protein interactions are major driving forces behind the functional phenotypes of biological
processes. As such, evolutionary footprints are reflected in system-level collections of …

Viruses are one of the major causes of acute and chronic infectious diseases and thus a
major contributor to the global burden of disease. Several studies have shown how viruses …

The current therapeutic arsenal against viral infections remains limited, with often poor
efficacy and incomplete coverage, and appears inadequate to face the emergence of drug …