The ability of the human fungal pathogen Cryptococcus neoformans to adapt to variable
copper (Cu) environments within the host is key for successful dissemination and …

Copper (Cu) is an essential metal that is toxic at high concentrations. Thus, pathogens often
rely on host Cu for growth, but host cells can hyperaccumulate Cu to exert antimicrobial …

Cryptococcus neoformans is a human fungal pathogen that is the causative agent of
cryptococcosis and fatal meningitis in immuno‐compromised hosts. Recent studies suggest …

While research has identified an important contribution for metals, such as iron, in microbial
pathogenesis, the roles of other transition metals, such as copper, remain mostly unknown …

The study of regulatory networks in human pathogens such as Cryptococcus neoformans
provides insights into host-pathogen interactions that may allow for correlation of gene …

Cryptococcus neoformans is a major human pathogen and a cause of meningoencephalitis
in immunocompromised patients. Many factors contribute to the extraordinary survivability …

Copper homeostasis is important for virulence of the fungus Cryptococcus neoformans,
which can cause lethal meningoencephalitis in humans. Cryptococcus cells encounter high …

Copper (Cu) ions serve as catalytic cofactors to drive key biochemical processes, and yet Cu
levels that exceed cellular homeostatic control capacity are toxic. The underlying …

Cryptococcus neoformans is an opportunistic fungal pathogen whose pathogenic lifestyle is
linked to its ability to cope with fluctuating levels of copper (Cu), an essential metal involved …

Cryptococcus neoformans is a human opportunistic fungal pathogen responsible for∼ 1/3 of
HIV/AIDS deaths worldwide. This budding yeast expresses a polysaccharide capsule …