Pathogen‐induced inflammation at sites distant from oral infection: bacterial persistence and induction of cell‐specific innate immune inflammatory pathways

C Hayashi, CV Gudino, FC Gibson Iii… - Molecular oral …, 2010 - Wiley Online Library
A hallmark of infection with the gram‐negative pathogen Porphyromonas gingivalis is the
induction of a chronic inflammatory response. P. gingivalis induces a local chronic …

[PDF][PDF] Engagement of specific innate immune signaling pathways during Porphyromonas gingivalis induced chronic inflammation and atherosclerosis

G FC III - Front. Biosci., 2008 - article.imrpress.com
Introduction 3. Epidemiological Associations Of Infection With Systemic Diseases 3.1.
Infectious Agents And Association With Atherosclerosis 3.2. Periodontal Disease And P …

Innate Immune Signaling and Porphyromonas gingivalis-accelerated Atherosclerosis

FC Gibson III, H Yumoto, Y Takahashi… - Journal of dental …, 2006 - journals.sagepub.com
Periodontal diseases are a group of diseases that lead to erosion of the hard and soft
tissues of the periodontium, which, in severe cases, can result in tooth loss. Anecdotal …

Porphyromonas gingivalis lipopolysaccharide is poorly recognized by molecular components of innate host defense in a mouse model of early inflammation

RA Reife, RA Shapiro, BA Bamber, KK Berry… - Infection and …, 1995 - Am Soc Microbiol
Porphyromonas gingivalis is a gram-negative bacterium that is associated with periodontitis.
It has been hypothesized that destruction of bone and periodontal connective tissue is …

Porphyromonas gingivalis suppresses adaptive immunity in periodontitis, atherosclerosis, and Alzheimer's disease

I Olsen, MA Taubman, SK Singhrao - Journal of oral microbiology, 2016 - Taylor & Francis
Porphyromonas gingivalis, a keystone pathogen in chronic periodontitis, has been found to
associate with remote body organ inflammatory pathologies, including atherosclerosis and …

Porphyromonas gingivalis-Epithelial Cell Interactions in Periodontitis

E Andrian, D Grenier… - Journal of dental …, 2006 - journals.sagepub.com
Emerging data on the consequences of the interactions between invasive oral bacteria and
host cells have provided new insights into the pathogenesis of periodontal disease. Indeed …

Local and Systemic Effects of Porphyromonas gingivalis Infection

WA Chen, Y Dou, HM Fletcher, DS Boskovic - Microorganisms, 2023 - mdpi.com
Porphyromonas gingivalis, a gram-negative anaerobe, is a leading etiological agent in
periodontitis. This infectious pathogen can induce a dysbiotic, proinflammatory state within …

Breaking bad: Manipulation of the host response by Porphyromonas gingivalis

G Hajishengallis, RJ Lamont - European journal of immunology, 2014 - Wiley Online Library
Recent metagenomic and mechanistic studies are consistent with a new model of
periodontal pathogenesis. This model proposes that periodontal disease is initiated by a …

Porphyromonas gingivalis Lipopolysaccharide Displays Functionally Diverse Interactions With the Innate Host Defense System

BW Bainbridge, SR Coats… - Annals of …, 2002 - Wiley Online Library
Periodontitis is a bacterially induced chronic inflammatory disease and a major cause of
tooth loss in the world. The tissue damage and alveolar bone resorption characteristic of the …

Porphyromonas gingivalis: Immune Subversion Activities and Role in Periodontal Dysbiosis

G Hajishengallis, PI Diaz - Current oral health reports, 2020 - Springer
Abstract Purpose of Review This review summarizes mechanisms by which Porphyromonas
gingivalis interacts with community members and the host so that it can persist in the …