Host NOD-like receptor family pyrin domain-containing 6 (NLRP6) regulates innate immune
responses and gastrointestinal homeostasis. Its protective role in intestinal colitis and …

Inflammatory bowel diseases involve the dynamic interaction of host genetics, the
microbiome and inflammatory responses. Here we found lower expression of NLRP12 …

Identification of the individual factors contributing to the formation of ''healthy''or disease-
modulating ''dysbiotic''microbiome communities is an important aspect of microbiome …

NLRP6 is a Nod-like receptor expressed in the intestinal epithelium. Previous studies
reported a protective role for NLRP6 against intestinal injury and colitis-associated …

There has been significant interest in understanding how interactions between the host
immune system and the gut microbiota regulate intestinal homeostasis. Recent data suggest …

Inflammasomes are involved in gut homeostasis and inflammatory pathologies, but the role
of NLRP3 inflammasome in these processes is not well understood. Cryopyrin-associated …

The inflammasomes have an important role in connecting the detection of endogenous and
microbial danger signals to caspase-1 activation and induction of protective immune …

Dysfunction in host immune responses and pathologic alterations in the gut microbiota,
referred to as dysbiosis, can both contribute to the development of inflammatory bowel …

Introduction Gut microbiota have been linked to modulating susceptibility to Type 1 diabetes;
however, there are many ways in which the microbiota interact with host cells, including …

Patients with gluten sensitivities present with dysbiosis of the gut microbiome that is further
exacerbated by a strict adherence to a gluten-free diet (GFD). A subtype of patients …