Human cytomegalovirus (HCMV) is the most common cause of congenital infections and is
an important pathogen in immunocompromised individuals. Despite a robust host immune …

Human cytomegalovirus (HCMV) has become a paradigm for viral immune evasion due to
its unique multitude of immune-modulatory strategies. HCMV modulates the innate as well …

Human cytomegalovirus (HCMV) is ubiquitously prevalent. HCMV infection is typically
asymptomatic and controlled by the immune system in healthy individuals, yet HCMV can be …

Cytomegalovirus (CMV) has successfully established a long-lasting latent infection in
humans due to its ability to counteract the host antiviral innate immune response. During …

Human cytomegalovirus (hCMV) has evolved multiple mechanisms to escape the host
immune recognition and innate or adaptive immune responses. Among them, hCMV has …

The human cytomegalovirus (HCMV) has dedicated a significant part of its genome to genes
encoding molecules that modulate the host immune response. Many of these genes have …

The human cytomegalovirus (HCMV), whose genome is 235±1.9 kbp long, is a common
herpesvirus. However, the functions of many of its genes are still unknown. HCMV is closely …

CD58 is an adhesion molecule that is known to play a critical role in costimulation of effector
cells and is intrinsic to immune synapse structure. Herein, we describe a virally encoded …

Members of the Herpesviridae family have the capacity to undergo both lytic and latent
infection to establish a lifelong relationship with their host. Following primary infection …

Human cytomegalovirus (HCMV) infection induces both innate immune responses including
Natural Killer cells as well as adaptive humoral and cell mediated (CD4+ helper, CD8+ …