γδT cells elicited by CMV reactivation after allo-SCT cross-recognize CMV and leukemia

W Scheper, S van Dorp, S Kersting, F Pietersma… - Leukemia, 2013 - nature.com
Human cytomegalovirus (CMV) infections and relapse of disease remain major problems
after allogeneic stem cell transplantation (allo-SCT), in particular in combination with CMV …

The role of Vδ2-negative γδ T cells during cytomegalovirus reactivation in recipients of allogeneic stem cell transplantation

A Knight, AJ Madrigal, S Grace… - Blood, The Journal …, 2010 - ashpublications.org
Reactivation of cytomegalovirus (CMV) remains a serious complication after allogeneic stem
cell transplantation, but the role of γδ T cells is undefined. We have studied the immune …

Long-term expansion of effector/memory Vδ2 γδ T cells is a specific blood signature of CMV infection

V Pitard, D Roumanes, X Lafarge… - Blood, The Journal …, 2008 - ashpublications.org
The ability of human γδ T cells to develop immunologic memory is still a matter of debate.
We previously demonstrated the involvement of Vδ2− γδ T lymphocytes in the response of …

Control of murine cytomegalovirus infection by γδ T cells

S Sell, M Dietz, A Schneider, R Holtappels… - PLoS …, 2015 - journals.plos.org
Infections with cytomegalovirus (CMV) can cause severe disease in immunosuppressed
patients and infected newborns. Innate as well as cellular and humoral adaptive immune …

Implication of γδ T cells in the human immune response to cytomegalovirus

J Déchanet, P Merville, A Lim, C Retière… - The Journal of …, 1999 - Am Soc Clin Investig
In normal individuals, γδ T cells account for less than 6% of total peripheral T lymphocytes
and mainly express T-cell receptor (TCR) Vδ2-Vγ9 chains. We have previously observed a …

γδ T cell-mediated immunity to cytomegalovirus infection

C Khairallah, J Déchanet-Merville… - Frontiers in …, 2017 - frontiersin.org
γδ T lymphocytes are unconventional immune cells, which have both innate-and adaptive-
like features allowing them to respond to a wide spectrum of pathogens. For many years, we …

Cytomegalovirus reactivation following allogeneic stem cell transplantation is associated with the presence of dysfunctional antigen-specific CD8+ T cells

E Özdemir, LS St. John, G Gillespie… - Blood, The Journal …, 2002 - ashpublications.org
Cytomegalovirus (CMV) infection causes significant morbidity and mortality in the setting of
immunodeficiency, including the immune reconstitution phase following allogeneic stem cell …

Common Features of γδ T Cells and CD8+ αβ T Cells Responding to Human Cytomegalovirus Infection in Kidney Transplant Recipients

L Couzi, V Pitard, S Netzer, I Garrigue… - The Journal of …, 2009 - academic.oup.com
Background Kidney transplant recipients infected with cytomegalovirus (CMV) undergo a
persistent γδ T cell expansion in their peripheral blood. The anti-CMV function of these cells …

Levels of CMV specific CD4 T cells are dynamic and correlate with CMV viremia after allogeneic stem cell transplantation

T Widmann, U Sester, BC Gärtner, J Schubert… - PloS one, 2008 - journals.plos.org
Cytomegalovirus (CMV) infection is the most frequent viral complication in patients after
allogeneic stem cell transplantation. As CMV replication is tightly controlled by the cellular …

Potential beneficial effects of cytomegalovirus infection after transplantation

NHR Litjens, L van der Wagen, J Kuball… - Frontiers in …, 2018 - frontiersin.org
Cytomegalovirus (CMV) infection can cause significant complications after transplantation,
but recent emerging data suggest that CMV may paradoxically also exert beneficial effects in …