Antiparkinsonian agents in investigational polymeric micro-and Nano-Systems
N Paccione, M Rahmani, E Barcia, S Negro - Pharmaceutics, 2022 - mdpi.com
Parkinson's disease (PD) is a devastating neurodegenerative disease characterized by
progressive destruction of dopaminergic tissue in the central nervous system (CNS). To …
progressive destruction of dopaminergic tissue in the central nervous system (CNS). To …
Polymeric nanoparticles for dopamine and levodopa replacement in Parkinson's disease
OAA Alabrahim, HMES Azzazy - Nanoscale advances, 2022 - pubs.rsc.org
As the world's population ages, the incidence of Parkinson's disease (PD), the second most
common neurological ailment, keeps increasing. It is estimated that 1% of the global …
common neurological ailment, keeps increasing. It is estimated that 1% of the global …
Micro-and nanotechnology approaches to improve Parkinson's disease therapy
PV Torres-Ortega, L Saludas, AS Hanafy… - Journal of controlled …, 2019 - Elsevier
Current therapies for Parkinson's disease are symptomatic and unable to regenerate the
brain tissue. In recent years, the therapeutic potential of a wide variety of neuroprotective …
brain tissue. In recent years, the therapeutic potential of a wide variety of neuroprotective …
Importance of nanoparticles for the delivery of antiparkinsonian drugs
Parkinson's disease (PD) affects around ten million people worldwide and is considered the
second most prevalent neurodegenerative disease after Alzheimer's disease. In addition …
second most prevalent neurodegenerative disease after Alzheimer's disease. In addition …
Prospects for polymer therapeutics in Parkinson's disease and other neurodegenerative disorders
Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons
and represents a growing health burden to western societies. Like many neurodegenerative …
and represents a growing health burden to western societies. Like many neurodegenerative …
Nanomedicine to overcome current Parkinson's treatment liabilities: A systematic review
GH Hawthorne, MP Bernuci, M Bortolanza… - Neurotoxicity …, 2016 - Springer
Nanoparticles might be produced and manipulated to present a large spectrum of
properties. The physicochemical features of the engineered nanomaterials confer to them …
properties. The physicochemical features of the engineered nanomaterials confer to them …
Parkinson's disease: Current drug therapy and unraveling the prospects of nanoparticles
A Paul, KS Yadav - Journal of Drug Delivery Science and Technology, 2020 - Elsevier
Abstract Parkinson's disease (PD), although being the second most prevalent
neurodegenerative disease (ND) encounters lack of definitive treatment and challenges in …
neurodegenerative disease (ND) encounters lack of definitive treatment and challenges in …
Drug development in Parkinson's disease: from emerging molecules to innovative drug delivery systems
E Garbayo, E Ansorena, MJ Blanco-Prieto - Maturitas, 2013 - Elsevier
Current treatments for Parkinson's disease (PD) are aimed at addressing motor symptoms
but there is no therapy focused on modifying the course of the disease. Successful treatment …
but there is no therapy focused on modifying the course of the disease. Successful treatment …
A neoteric annotation on the advances in combination therapy for Parkinson's disease: nanocarrier-based combination approach and future anticipation. Part II …
Introduction The current treatment modalities available for Parkinson's disease (PD) prove
inadequate due to the inherent constraints in effectively transporting bioactive compounds …
inadequate due to the inherent constraints in effectively transporting bioactive compounds …
Boosting drug discovery for Parkinson's: enhancement of the delivery of a monoamine oxidase-B inhibitor by brain-targeted PEGylated polycaprolactone-based …
The current pharmacological treatments for Parkinson's disease only offer symptomatic relief
to the patients and are based on the administration of levodopa and catechol-O …
to the patients and are based on the administration of levodopa and catechol-O …