Materials and Methods: After institutional approval and written consent, 14 healthy volunteer
participated in this study. Five vessels on the dorsum of hand of subjects were randomly …

Objectives Lidocaine spray is an effective analgesic of mucous membranes. Lidocaine spray
is also used during intravenous (iv) cannulation, especially in children. However, the …

Insertion of a peripheral IV cannula is a common, although painful, procedure. We tested the
analgesic efficacy, adverse effects, and cost-effectiveness of a needle-free intradermal drug …

Arterial cannulation through the standard skin wheal of local anesthetic raised with a needle
may be painful. The authors compared the efficacy of local anesthetic injected via a 25G …

To evaluate patients' perceptions and preferences concerning pain control during
intravenous (IV) catheterization, a sample of 50 adult patients received subcutaneous …

Objectives: The objectives were to determine whether pretreatment with needleless jet‐
delivered lidocaine decreases self‐reported pain in children undergoing needle insertion in …

Study Objective: To compare efficacy and cost of lidocaine cutaneous anesthesia by two jet
injectors to routine needle infiltration for pain relief of intravenous (IV) catheterization …

In this study we evaluated whether a lidocaine patch reduces the pain relating to a venous
cannulation in adults. The patch is consisted of the base containing 50% lidocaine on a thin …

Objective: This study aimed to compare the efficacies of two different topical anesthetic
agents and placebo in the reduction of the pain observed during intravenous (IV) …

Pain is the unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Early pain experiences due to IV cannulation, may play a vital role in …