Obesity induces ovarian inflammation and reduces oocyte quality
In the United States, 36.5% of women between the ages of 20 and 39 years are obese. This
obesity results in not only metabolic disorders including type II diabetes and cardiovascular …
obesity results in not only metabolic disorders including type II diabetes and cardiovascular …
Inflammatory pathways linking obesity and ovarian dysfunction
This review summarizes some of the recent advances in obesity research and describes
how we and others have built upon these findings to better understand the impact of obesity …
how we and others have built upon these findings to better understand the impact of obesity …
Inflammation and human ovarian follicular dynamics
CE Boots, ES Jungheim - Seminars in reproductive medicine, 2015 - thieme-connect.com
Inflammation is a biologic process that mediates tissue effects including vasodilation,
hyperemia, edema, collagenolysis, and cell proliferation through complex immunologic …
hyperemia, edema, collagenolysis, and cell proliferation through complex immunologic …
Obesity modulates inflammation and lipid metabolism oocyte gene expression: a single-cell transcriptome perspective
ML Ruebel, M Cotter, CR Sims… - The Journal of …, 2017 - academic.oup.com
Context: It is hypothesized that obesity adversely affects the ovarian environment, which can
disrupt oocyte maturation and embryonic development. Objective: This study aimed to …
disrupt oocyte maturation and embryonic development. Objective: This study aimed to …
Pathophysiological roles of chronic low‐grade inflammation mediators in polycystic ovary syndrome
M Rostamtabar, S Esmaeilzadeh… - Journal of cellular …, 2021 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is the most common hormonal imbalance disease in
reproductive‐aged women. Its basic characteristics are ovulatory dysfunction and ovarian …
reproductive‐aged women. Its basic characteristics are ovulatory dysfunction and ovarian …
Role of hormonal and inflammatory alterations in obesity-related reproductive dysfunction at the level of the hypothalamic-pituitary-ovarian axis
M Goldsammler, Z Merhi, E Buyuk - Reproductive Biology and …, 2018 - Springer
Background Besides being a risk factor for multiple metabolic disorders, obesity could affect
female reproduction. While increased adiposity is associated with hormonal changes that …
female reproduction. While increased adiposity is associated with hormonal changes that …
Female reproductive dysfunctions and the gut microbiota
SB Chadchan, V Singh… - Journal of molecular …, 2022 - jme.bioscientifica.com
The gut microbiome is considered an endocrine organ that can influence distant organs and
associated biological pathways. Recent advances suggest that gut microbial homeostasis is …
associated biological pathways. Recent advances suggest that gut microbial homeostasis is …
Development of mammalian ovary
Obesity is an ongoing pandemic and serves as a causal factor of a wide spectrum of
metabolic diseases including diabetes, fatty liver disease, and cardiovascular disease. Much …
metabolic diseases including diabetes, fatty liver disease, and cardiovascular disease. Much …
Inflammation in polycystic ovary syndrome: underpinning of insulin resistance and ovarian dysfunction
F González - Steroids, 2012 - Elsevier
Chronic low-grade inflammation has emerged as a key contributor to the pathogenesis of
Polycystic Ovary Syndrome (PCOS). A dietary trigger such as glucose is capable of inciting …
Polycystic Ovary Syndrome (PCOS). A dietary trigger such as glucose is capable of inciting …
Role of gut microbiota in the development of insulin resistance and the mechanism underlying polycystic ovary syndrome: a review
F He, Y Li - Journal of ovarian research, 2020 - Springer
Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder.
Typically, it is characterized by hirsutism, hyperandrogenism, ovulatory dysfunction …
Typically, it is characterized by hirsutism, hyperandrogenism, ovulatory dysfunction …