Accounting for bias in the estimation of r2 between two sets of noisy neural responses

DA Pospisil, W Bair - Journal of Neuroscience, 2022 - Soc Neuroscience
The Pearson correlation coefficient squared, r 2, is an important tool used in the analysis of
neural data to quantify the similarity between neural tuning curves. Yet this metric is biased …

Accounting for biases in the estimation of neuronal signal correlation

DA Pospisil, W Bair - Journal of Neuroscience, 2021 - Soc Neuroscience
Signal correlation (rs) is commonly defined as the correlation between the tuning curves of
two neurons and is widely used as a metric of tuning similarity. It is fundamental to how …

The unbiased estimation of the fraction of variance explained by a model

DA Pospisil, W Bair - PLoS computational biology, 2021 - journals.plos.org
The correlation coefficient squared, r 2, is commonly used to validate quantitative models on
neural data, yet it is biased by trial-to-trial variability: as trial-to-trial variability increases …

Relating divisive normalization to neuronal response variability

R Coen-Cagli, SS Solomon - Journal of Neuroscience, 2019 - Soc Neuroscience
Cortical responses to repeated presentations of a sensory stimulus are variable. This
variability is sensitive to several stimulus dimensions, suggesting that it may carry useful …

Neural response variability and divisive normalization

R Coen-Cagli, SS Solomon - bioRxiv, 2018 - biorxiv.org
Cortical responses to repeated presentations of a stimulus are variable. This variability is
sensitive to experimental manipulations that are also known to engage divisive …

[HTML][HTML] Characterizing the nonlinear structure of shared variability in cortical neuron populations using latent variable models

MR Whiteway, K Socha, V Bonin… - Neurons, behavior, data …, 2019 - ncbi.nlm.nih.gov
Sensory neurons often have variable responses to repeated presentations of the same
stimulus, which can significantly degrade the stimulus information contained in those …

Characterizing the nonlinear structure of shared variability in cortical neuron populations using neural networks

MR Whiteway, K Socha, V Bonin, DA Butts - bioRxiv, 2018 - biorxiv.org
Sensory neurons often have variable responses to repeated presentations of the same
stimulus. Simultaneous recordings of neural populations demonstrate that such variability is …

Measuring the performance of neural models

O Schoppe, NS Harper, BDB Willmore… - Frontiers in …, 2016 - frontiersin.org
Good metrics of the performance of a statistical or computational model are essential for
model comparison and selection. Here, we address the design of performance metrics for …

Dethroning the fano factor: a flexible, model-based approach to partitioning neural variability

AS Charles, M Park, JP Weller, GD Horwitz… - Neural …, 2018 - direct.mit.edu
Neurons in many brain areas exhibit high trial-to-trial variability, with spike counts that are
overdispersed relative to a Poisson distribution. Recent work (Goris, Movshon, & …

Model-based characterization of the selectivity of neurons in primary visual cortex

F Bartsch, BG Cumming… - Journal of …, 2022 - journals.physiology.org
Statistical models are increasingly being used to understand the complexity of stimulus
selectivity in primary visual cortex (V1) in the context of complex time-varying stimuli …