FOXO3-induced oncogenic lncRNA CASC9 enhances gefitinib resistance of non-small-cell lung cancer through feedback loop
Z Bing, J Han, Z Zheng, N Liang - Life Sciences, 2021 - Elsevier
Gefitinib is tyrosine kinase inhibitor of epidermal growth factor receptor, which exhibits
notable clinical efficacy in non-small-cell lung cancer (NSCLC) treatment. However, gefitinib …
notable clinical efficacy in non-small-cell lung cancer (NSCLC) treatment. However, gefitinib …
Long non-coding RNA CASC9 promotes gefitinib resistance in NSCLC by epigenetic repression of DUSP1
Z Chen, Q Chen, Z Cheng, J Gu, W Feng, T Lei… - Cell Death & …, 2020 - nature.com
Resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), such
as gefitinib, has greatly affected clinical outcomes in non-small cell lung cancer (NSCLC) …
as gefitinib, has greatly affected clinical outcomes in non-small cell lung cancer (NSCLC) …
[HTML][HTML] LncRNA OSER1-AS1 interacts with miR-612/FOXM1 axis to modulate gefitinib resistance of lung adenocarcinoma
T Shi, W Sun, YL Shi, Q Wang, ZX Yan… - American journal of …, 2021 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) play crucial roles in the acquired resistance to EGFR-
directed therapies in lung cancer. LncRNA OSER1-AS1 has been reported to promote …
directed therapies in lung cancer. LncRNA OSER1-AS1 has been reported to promote …
lncRNA FOXD2-AS1 confers cisplatin resistance of non-small-cell lung cancer via regulation of miR185-5p–SIX1 axis
P Ge, L Cao, YJ Yao, RJ Jing, W Wang… - OncoTargets and …, 2019 - Taylor & Francis
Background Chemoresistance is a major obstacle for chemotherapy failure in non-small-cell
lung cancer (NSCLC). lncRNAs are a class of pivotal regulators in various cancers, and the …
lung cancer (NSCLC). lncRNAs are a class of pivotal regulators in various cancers, and the …
FOXC1-mediated LINC00301 facilitates tumor progression and triggers an immune-suppressing microenvironment in non-small cell lung cancer by regulating the …
CC Sun, W Zhu, SJ Li, W Hu, J Zhang, Y Zhuo… - Genome medicine, 2020 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) are extensively intricate in the
tumorigenesis and metastasis of various cancer types. Nevertheless, the detailed molecular …
tumorigenesis and metastasis of various cancer types. Nevertheless, the detailed molecular …
lncRNA CCAT1 acts as a MicroRNA-218 sponge to increase gefitinib resistance in NSCLC by targeting HOXA1
X Jin, X Liu, Z Zhang, Y Guan - Molecular Therapy-Nucleic Acids, 2020 - cell.com
Long non-coding RNA (lncRNA) colon cancer-associated transcript-1 (CCAT1) has been
reported to play important roles in the development and progression of multiple human …
reported to play important roles in the development and progression of multiple human …
Transcriptome analysis of EGFR tyrosine kinase inhibitors resistance associated long noncoding RNA in non-small cell lung cancer
P Ma, M Zhang, F Nie, Z Huang, J He, W Li… - Biomedicine & …, 2017 - Elsevier
The non–small cell lung cancer (NSCLC) patients harbor mutations in the epidermal growth
factor receptor (EGFR) can be therapeutically targeted by EGFR tyrosine kinase inhibitors …
factor receptor (EGFR) can be therapeutically targeted by EGFR tyrosine kinase inhibitors …
Upregulated lncRNA CASC9 contributes to progression of non-small cell lung cancer through inhibition of miR-335-3p and activation S100A14 expression
W Zhao, T Chen, Y Zhao - OncoTargets and therapy, 2020 - Taylor & Francis
Introduction Non-small cell lung cancer (NSCLC) is a deadly cancer type worldwide and the
main sub-type of lung cancer. Cancer susceptibility candidate-9 (CASC9) was reported to be …
main sub-type of lung cancer. Cancer susceptibility candidate-9 (CASC9) was reported to be …
[HTML][HTML] Silencing of CASC8 inhibits non-small cell lung cancer cells function and promotes sensitivity to osimertinib via FOXM1
X Jiang, J Guan, XU Yitong, H Ren, J Jiang… - Journal of …, 2021 - ncbi.nlm.nih.gov
In a meta-analysis, the long noncoding RNA cancer susceptibility candidate 8 (CASC8) was
found to be a cancer susceptibility gene closely related to lung cancer, but its functions in …
found to be a cancer susceptibility gene closely related to lung cancer, but its functions in …
The positive feedback loop FOXO3/CASC11/miR-498 promotes the tumorigenesis of non-small cell lung cancer
R Yan, Y Jiang, B Lai, Y Lin, J Wen - Biochemical and Biophysical …, 2019 - Elsevier
An increasing number of studies have indicated that long noncoding RNAs (lncRNAs) are
involved in the regulation of non-small-cell lung cancer (NSCLC). Nevertheless, there are …
involved in the regulation of non-small-cell lung cancer (NSCLC). Nevertheless, there are …
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