β-Blockers, heart disease and COPD: current controversies and uncertainties

JG Baker, RG Wilcox - Thorax, 2017 - thorax.bmj.com
Treating people with cardiovascular disease and COPD causes significant clinician anxiety.
β-Blockers save lives in people with heart disease, specifically postinfarction and heart …

Role of beta-blockers in patients with COPD: current perspective

M Malerba, P Montuschi, A Radaeli, M Pirisi - Drug discovery today, 2015 - Elsevier
Highlights•Selective BBs in COPD were not associated with relevant worsening of
pulmonary function.•Selective BBs could be used in COPD with CVD comorbidities.•In …

Beta-blockers in COPD: time for reappraisal

B Lipworth, J Wedzicha, G Devereux… - European …, 2016 - Eur Respiratory Soc
The combined effects on the heart of smoking and hypoxaemia may contribute to an
increased cardiovascular burden in chronic obstructive pulmonary disease (COPD). The use …

Beta-blocker therapy of cardiovascular diseases in patients with bronchial asthma or COPD: the pro viewpoint

H Ashrafian, AG Violaris - Primary care respiratory journal, 2005 - nature.com
Extensive randomised clinical trial (datasupportthe view that β-blockers have a significant
impact opífdíQpd s of patients with cardiovascular disease, especially those with coronary …

Beta-blockers use in patients with chronic obstructive pulmonary disease and concomitant cardiovascular conditions

K Albouaini, M Andron, A Alahmar… - International journal of …, 2007 - Taylor & Francis
The mortality and incidence of chronic obstructive pulmonary disease (COPD) and coronary
heart disease increase with age. Despite the clear evidence of beta blockers (BBs) …

Cardiovascular effects of β-agonists in patients with asthma and COPD: a meta-analysis

SR Salpeter, TM Ormiston, EE Salpeter - Chest, 2004 - Elsevier
Background β-Adrenergic agonists exert physiologic effects that are the opposite of those of
β-blockers. β-Blockers are known to reduce morbidity and mortality in patients with cardiac …

[HTML][HTML] β-Blockers in COPD: a cohort study from the TONADO Research Program

F Maltais, R Buhl, A Koch, VC Amatto, J Reid, L Grönke… - Chest, 2018 - Elsevier
Background Cardiovascular disease is a frequent comorbidity in patients with COPD. Many
physicians, particularly pulmonologists, are reluctant to use β-adrenoceptor blocking agents …

Use of β-blockers in patients with COPD

MR Andrus, KP Holloway… - Annals of …, 2004 - journals.sagepub.com
OBJECTIVE: To evaluate the safety and cardiovascular benefits of β-blocker therapy in
patients with chronic obstructive pulmonary disease (COPD). DATA SOURCES: Clinical …

Detrimental effects of β-blockers in COPD: a concern for nonselective β-blockers

HJ van der Woude, J Zaagsma, DS Postma, TH Winter… - Chest, 2005 - Elsevier
Introduction β-Blockers are known to worsen FEV 1 and airway hyperresponsiveness (AHR)
in patients with asthma. Both characteristics determine the outcome of COPD, a disease with …

β-blocker therapy and clinical outcomes in patients with moderate chronic obstructive pulmonary disease and heightened cardiovascular risk. An observational …

MT Dransfield, DA McAllister, JA Anderson… - Annals of the …, 2018 - atsjournals.org
Rationale: Cardiovascular disease is a common comorbidity in patients with chronic
obstructive pulmonary disease. Although β-blockers can be used safely in patients with …