[HTML][HTML] N-myc downstream-regulated gene 2, a novel estrogen-targeted gene, is involved in the regulation of Na+/K+-ATPase

Y Li, J Yang, S Li, J Zhang, J Zheng, W Hou… - Journal of Biological …, 2011 - ASBMB
Na+/K+-ATPase, a plasma membrane protein abundantly expressed in epithelial tissues,
has been identified and linked to numerous biological events, including ion transport and …

[HTML][HTML] The expression and localization of N-myc downstream-regulated gene 1 in human trophoblasts

XH Shi, JC Larkin, B Chen, Y Sadovsky - PloS one, 2013 - journals.plos.org
The protein N-Myc downstream-regulated gene 1 (NDRG1) is implicated in the regulation of
cell proliferation, differentiation, and cellular stress response. NDRG1 is expressed in …

Expression of NDRG1, a differentiation-related gene, in human tissues

P Lachat, P Shaw, S Gebhard, N van Belzen… - Histochemistry and cell …, 2002 - Springer
NDRG1 is a member of the new N-myc downregulated gene (NDRG) family which belongs
to the α/β hydrolase superfamily, but without presenting a hydrolytic catalytic site. Diverse …

[HTML][HTML] N-myc down-regulated gene 1 modulates the response of term human trophoblasts to hypoxic injury

B Chen, DM Nelson, Y Sadovsky - Journal of Biological Chemistry, 2006 - ASBMB
The placenta is susceptible to diverse insults during human pregnancy. The expression of
the protein N-myc down-regulated gene 1 (NDRG1) is regulated during cell proliferation …

[HTML][HTML] Global gene expression analysis reveals a link between NDRG1 and vesicle transport

HA Askautrud, E Gjernes, G Gunnes, M Sletten… - PLoS …, 2014 - journals.plos.org
N-myc downstream-regulated gene 1 (NDRG1) is induced by cellular stress such as hypoxia
and DNA damage, and in humans, germ line mutations cause Charcot-Marie-Tooth disease …

[HTML][HTML] Physical interactions and functional coupling between Daxx and sodium hydrogen exchanger 1 in ischemic cell death

YS Jung, HY Kim, J Kim, MG Lee, J Pouysségur… - Journal of biological …, 2008 - ASBMB
Daxx, a death domain-associated protein, is implicated in ischemic cell death. To clarify the
mechanism of cell death mediated by Daxx, a yeast two-hybrid assay was performed …

[HTML][HTML] Differential expression and hypoxia‐mediated regulation of the N‐myc downstream regulated gene family

N Le, TM Hufford, JS Park, RM Brewster - The FASEB Journal, 2021 - ncbi.nlm.nih.gov
Many organisms rely on oxygen to generate cellular energy (adenosine triphosphate or
ATP). During severe hypoxia, the production of ATP decreases, leading to cell damage or …

[HTML][HTML] Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor

J Hwang, Y Kim, HB Kang, L Jaroszewski… - Journal of Biological …, 2011 - ASBMB
Considerable attention has recently been paid to the N-Myc downstream-regulated gene
(NDRG) family because of its potential as a tumor suppressor in many human cancers …

[HTML][HTML] Hypoxia increases cytoplasmic expression of NDRG1, but is insufficient for its membrane localization in human hepatocellular carcinoma

S Sibold, V Roh, A Keogh, P Studer, C Tiffon, E Angst… - FEBS letters, 2007 - Elsevier
NDRG1 is a hypoxia-inducible protein, whose modulated expression is associated with the
progression of human cancers. Here, we reveal that NDRG1 is markedly upregulated in the …

Cellular distribution of NDRG1 protein in the rat kidney and brain during normal postnatal development

Y Wakisaka, A Furuta, K Masuda… - … of Histochemistry & …, 2003 - journals.sagepub.com
N-myc downregulated gene 1 (NDRG1) is a 43-kD protein whose mRNA is induced by DNA
damage, hypoxia, or prolonged elevation of intracellular calcium. Although NDRG1 is also …