[HTML][HTML] CYP51 Mutations in the Fusarium solani Species Complex: First Clue to Understand the Low Susceptibility to Azoles of the Genus Fusarium
P Vermeulen, A Gruez, AL Babin, JP Frippiat… - Journal of Fungi, 2022 - mdpi.com
Members of Fusarium solani species complex (FSSC) are cosmopolitan filamentous fungi
responsible for invasive fungal infections in immunocompromised patients. Despite the …
responsible for invasive fungal infections in immunocompromised patients. Despite the …
Overinduction of CYP51A Gene After Exposure to Azole Antifungals Provides a First Clue to Resistance Mechanism in Fusarium solani Species Complex
M d'Agostino, T Lemmet, C Dufay, A Luc… - Microbial Drug …, 2018 - liebertpub.com
The genus Fusarium is largely represented in fungal infections, not only mostly in plants but
also in humans. Fungi belonging to the Fusarium solani species complex (FSSC) are those …
also in humans. Fungi belonging to the Fusarium solani species complex (FSSC) are those …
[HTML][HTML] Azole Resistance and cyp51A Mutation of Aspergillus fumigatus in a Tertiary Referral Hospital in Taiwan
TH Hsu, PY Huang, YC Fan, PL Sun - Journal of Fungi, 2022 - mdpi.com
Azole resistance in Aspergillus fumigatus has increasingly been reported worldwide. Its
major mechanism of resistance is mediated by mutations in cyp51A. The objective of this …
major mechanism of resistance is mediated by mutations in cyp51A. The objective of this …
[HTML][HTML] Exploring the Potential Mechanism of Prothioconazole Resistance in Fusarium graminearum in China
F Zhou, A Han, Y Jiao, Y Cao, L Wang, H Hu, R Liu… - Journal of Fungi, 2023 - mdpi.com
The Fusarium head blight (FHB) caused by Fusarium graminearum is one of the most
important diseases threatening wheat production in China. However, the triazole sterol 14α …
important diseases threatening wheat production in China. However, the triazole sterol 14α …
[HTML][HTML] Contribution of NADPH-cytochrome P450 Reductase to Azole Resistance in Fusarium oxysporum
D He, Z Feng, S Gao, Y Wei, S Han… - Frontiers in Microbiology, 2021 - frontiersin.org
Fusarium species exhibit significant intrinsic resistance to most antifungal agents and
fungicides, resulting in high mortality rates among immunocompromised patients …
fungicides, resulting in high mortality rates among immunocompromised patients …
Aspergillus fumigatus clinical isolates carrying CYP51A with TR34/L98H/S297T/F495I substitutions detected after four-year retrospective azole resistance screening in …
L Pontes, CAG Beraquet, T Arai, GL Pigolli… - Antimicrobial agents …, 2020 - Am Soc Microbiol
Azole antifungal resistance in Aspergillus fumigatus is a worldwide concern. As in most
public hospitals in Brazil, antifungal susceptibility tests are not routinely performed for …
public hospitals in Brazil, antifungal susceptibility tests are not routinely performed for …
Screening and Characterization of a Non-cyp51A Mutation in an Aspergillus fumigatus cox10 Strain Conferring Azole Resistance
The rapid and global emergence of azole resistance in the human pathogen Aspergillus
fumigatus has drawn attention. Thus, a thorough understanding of its mechanisms of drug …
fumigatus has drawn attention. Thus, a thorough understanding of its mechanisms of drug …
[HTML][HTML] A 23 bp cyp51A Promoter Deletion Associated With Voriconazole Resistance in Clinical and Environmental Isolates of Neocosmospora keratoplastica
In the fungal pathogen Aspergillus fumigatus, resistance to azole antifungals is often linked
to mutations in CYP51A, a gene that encodes the azole antifungal drug target lanosterol 14α …
to mutations in CYP51A, a gene that encodes the azole antifungal drug target lanosterol 14α …
Azole resistance in Aspergillus fumigatus: mechanisms, route of resistance selection, and clinical implications
S Seyedmousavi, P Verweij - 2017 - repub.eur.nl
The medical triazoles, itraconazole, voriconazole, and posaconazole, are the most widely
used drugs for the management of infections caused by the saprophytic mold Aspergillus …
used drugs for the management of infections caused by the saprophytic mold Aspergillus …
Genomic perspective of triazole resistance in clinical and environmental Aspergillus fumigatus isolates without cyp51A mutations
Aspergillus fumigatus is the most common etiologic agent of primarily all clinical
manifestations of aspergillosis. A steady increase in the number of azole resistant A …
manifestations of aspergillosis. A steady increase in the number of azole resistant A …