DNA methylation in mammals
E Li, Y Zhang - Cold Spring Harbor perspectives in …, 2014 - cshperspectives.cshlp.org
DNA methylation is one of the best characterized epigenetic modifications. In mammals it is
involved in various biological processes including the silencing of transposable elements …
involved in various biological processes including the silencing of transposable elements …
[PDF][PDF] The role of mammalian DNA methyltransferases in the regulation of gene expression
J Turek-Plewa, PP Jagodzinski - Cellular and Molecular Biology Letters, 2005 - Citeseer
The term epigenetic modification denotes reversible traits of gene expression that do not
include alterations to the DNA sequence. These epigenetic alterations are responsible for …
include alterations to the DNA sequence. These epigenetic alterations are responsible for …
Regulation of DNA methyltransferase 1 by interactions and modifications
W Qin, H Leonhardt, G Pichler - Nucleus, 2011 - Taylor & Francis
DNA methylation plays a central role in the epigenetic regulation of gene expression during
development and disease. Remarkably, the complex and changing patterns of genomic …
development and disease. Remarkably, the complex and changing patterns of genomic …
Biochemistry and biology of mammalian DNA methyltransferases
DNA methylation is a stable but not irreversible epigenetic signal that silences gene
expression. It has a variety of important functions in mammals, including control of gene …
expression. It has a variety of important functions in mammals, including control of gene …
An insight into the various regulatory mechanisms modulating human DNA methyltransferase 1 stability and function
DNA methylation is one of the principal epigenetic signals that participate in cell specific
gene expression in vertebrates. DNA methylation plays a quintessential role in the control of …
gene expression in vertebrates. DNA methylation plays a quintessential role in the control of …
[HTML][HTML] DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe
The mechanisms that establish and maintain methylation patterns in the mammalian
genome are very poorly understood, even though perturbations of methylation patterns lead …
genome are very poorly understood, even though perturbations of methylation patterns lead …
Interactions within the mammalian DNA methyltransferase family
JB Margot, AE Ehrenhofer-Murray, H Leonhardt - BMC molecular biology, 2003 - Springer
Background In mammals, epigenetic information is established and maintained via the
postreplicative methylation of cytosine residues by the DNA methyltransferases Dnmt1 …
postreplicative methylation of cytosine residues by the DNA methyltransferases Dnmt1 …
Dynamics of DNA methylation pattern
CL Hsieh - Current opinion in genetics & development, 2000 - Elsevier
Methylation patterns are the result of de novo methylation, demethylation, and the
maintenance of existing methylation. Although the existence and identity of an active …
maintenance of existing methylation. Although the existence and identity of an active …
Rethinking how DNA methylation patterns are maintained
DNA methylation patterns are set up early in mammalian development and are then copied
during the division of somatic cells. A long-established model for the maintenance of these …
during the division of somatic cells. A long-established model for the maintenance of these …