Mechanisms of particulate matter toxicity

Salvi, Holgate - Clinical & Experimental Allergy, 1999 - search.ebscohost.com
Discusses research studies on the biological mechanisms of particulate matter toxicity which
produce harmful effects on the lungs. Importance of exposure concentration of respirable …

Dust overloading of lungs: investigations of various materials, species differences, and irreversibility of effects

H Muhle, O Creutzenberg, B Bellmann… - Journal of Aerosol …, 1990 - liebertpub.com
In separate inhalation investigations, rodents (Wistar rats, Fischer-344 rats, Syrian golden
hamsters, NMRI and C57BL mice) were exposed to various dusts such as test toner …

Inhaled particles and respiratory disease

JE Salvaggio - Journal of Allergy and Clinical Immunology, 1994 - jacionline.org
This brief discussion of inhaled particles, their manner of deposition and clearance, and their
association with many human diseases has been designed to remind us of the importance …

Pulmonary toxicity of an atmospheric particulate sample is due to the soluble fraction

IYR Adamson, H Prieditis, R Vincent - Toxicology and applied …, 1999 - Elsevier
Adverse health effects have been associated with the inhalation of a variety of atmospheric
particles. The potential toxicity of a recently collected urban air particulate sample (EHC-93 …

Inhalable particles and pulmonary host defense: in vivo and in vitro effects of ambient air and combustion particles

GE Hatch, E Boykin, JA Graham, J Lewtas, F Pott… - Environmental …, 1985 - Elsevier
The ability of particulate air pollutants (and possible constituents) to alter pulmonary host
defenses was examined using an in vitro alveolar macrophage cytotoxicity assay and an in …

Particles causing lung disease.

KH Kilburn - Environmental health perspectives, 1984 - ehp.niehs.nih.gov
The lung has a limited number of patterns of reaction to inhaled particles. The disease
observed depends upon the location: conducting airways, terminal bronchioles and alveoli …

[图书][B] Pulmonary deposition and retention of inhaled aerosols

TF Hatch, P Gross - 2013 - books.google.com
Pulmonary Deposition and Retention of Inhaled Aerosols is concerned with the respiratory
deposition and retention of inhaled aerosols, starting with initial intake and concluding with …

Inhalation of poorly soluble particles. II. Influence of particle surface area on inflammation and clearance

CL Tran, D Buchanan, RT Cullen, A Searl… - Inhalation …, 2000 - Taylor & Francis
In this article the volumetric overload hypothesis, which predicts the impairment of clearance
of particles deposited in the lung in terms of particle volume, is reevaluated. The degree to …

Health effects of acute exposure to air pollution. Part II: Healthy subjects exposed to concentrated ambient particles.

ST Holgate, RB Devlin, SJ Wilson… - Research report (Health …, 2003 - europepmc.org
The purpose of this study was to assess the impact of short-term exposure to concentrated
ambient particles (CAPs*) on lung function and on inflammatory parameters in blood and …

Toxicological evidence for health effects from inhaled particulate pollution: Does it support the human experience?

RB Schlesinger - Inhalation toxicology, 1995 - Taylor & Francis
The fine size mode of ambient particulates, designated as PM-10, is a heterogeneous
mixture that can vary in particle size and chemical composition, depending on geographical …