Levofloxacin prophylaxis in patients with newly diagnosed myeloma (TEAMM): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial

MT Drayson, S Bowcock, T Planche, G Iqbal… - The Lancet …, 2019 - thelancet.com
Background Myeloma causes profound immunodeficiency and recurrent, serious infections.
Around 5500 new cases of myeloma are diagnosed per year in the UK, and a quarter of …

Oral antibiotic prophylaxis of early infection in multiple myeloma: a URCC/ECOG randomized phase III study

DH Vesole, MM Oken, C Heckler, PR Greipp, MS Katz… - Leukemia, 2012 - nature.com
Multiple myeloma (MM) is a malignancy of clonal plasma cells, resulting in an increased
production of ineffective immunoglobulins with suppression of non-involved …

Consensus guidelines and recommendations for infection prevention in multiple myeloma: a report from the International Myeloma Working Group

NS Raje, E Anaissie, SK Kumar, S Lonial… - The Lancet …, 2022 - thelancet.com
Infection remains the leading cause of morbidity and mortality in patients with multiple
myeloma because of the cumulative effect of disease, treatment, and host-related factors …

[HTML][HTML] Multiple myeloma and infections: a population-based study on 9253 multiple myeloma patients

C Blimark, E Holmberg, UH Mellqvist, O Landgren… - …, 2015 - ncbi.nlm.nih.gov
Infections are a major cause of morbidity and mortality in patients with multiple myeloma. To
estimate the risk of bacterial and viral infections in multiple myeloma patients, we used …

Infections in patients with multiple myeloma in the era of high-dose therapy and novel agents

M Nucci, E Anaissie - Clinical Infectious Diseases, 2009 - academic.oup.com
The introduction of stem cell transplantation and the novel anti-myeloma agents, bortezomib,
thalidomide, and lenalidomide, have improved the outcome of patients with multiple …

[HTML][HTML] Impact of prophylactic levofloxacin on rates of bloodstream infection and fever in neutropenic patients with multiple myeloma undergoing autologous …

MJ Satlin, S Vardhana, R Soave, TB Shore… - Biology of Blood and …, 2015 - Elsevier
Few studies have evaluated the role of antibacterial prophylaxis during neutropenia in
patients with multiple myeloma undergoing autologous hematopoietic stem cell …

The risk of infections in multiple myeloma before and after the advent of novel agents: a 12-year survey

A Brioli, M Klaus, H Sayer, S Scholl, T Ernst… - Annals of …, 2019 - Springer
Infections represent a major cause of morbidity and mortality in multiple myeloma and are
linked to both therapy-and disease-related factors. Although it has been suggested that the …

Prevention of infections including vaccination strategies in multiple myeloma

H Ludwig, S Kumar - American journal of hematology, 2023 - Wiley Online Library
Infections are a major cause of morbidity and mortality in multiple myeloma. The increased
risk for bacterial and viral infections results mainly from the disease‐inherent and treatment …

Management of infectious complications in multiple myeloma patients: Expert panel consensus-based recommendations

C Girmenia, M Cavo, M Offidani, F Scaglione, A Corso… - Blood Reviews, 2019 - Elsevier
The introduction of new therapeutic agents in multiple myeloma (MM), including proteasome
inhibitors, immunoregulatory drugs and monoclonal antibodies, has improved the outcomes …

Risks, severity and timing of infections in patients with multiple myeloma: a longitudinal cohort study in the era of immunomodulatory drug therapy

BW Teh, SJ Harrison, LJ Worth… - British journal of …, 2015 - Wiley Online Library
We defined the epidemiology and clinical predictors of infection in patients with multiple
myeloma (MM) receiving immunomodulatory drugs (IM iDs), proteasome inhibitors (PI) and …