New aspects of magnesium function: a key regulator in nucleosome self-assembly, chromatin folding and phase separation

T Ohyama - International journal of molecular sciences, 2019 - mdpi.com
Metal cations are associated with many biological processes. The effects of these cations on
nucleic acids and chromatin were extensively studied in the early stages of nucleic acid and …

Biochemistry of magnesium

K Pasternak, J Kocot, A Horecka - Journal of Elementology, 2010 - agro.icm.edu.pl
Magnesium is essential for biochemical functions of cells. Since Mg2+ has a relatively low
ionic radius in proportion to the size of the nucleus (0.86 versus 1.14 f A for Ca2+), it shows …

[PDF][PDF] Magnesium in cell proliferation and differentiation

FI Wolf, A Cittadini - Front Biosci, 1999 - Citeseer
Introduction 3. Mg content in proliferating and non-proliferating cells 4. The effect of
extracellular Mg on cell proliferation 5. The effect of extracellular Mg on the cell cycle 5.1 …

A transient rise in free Mg2+ ions released from ATP-Mg hydrolysis contributes to mitotic chromosome condensation

K Maeshima, T Matsuda, Y Shindo, H Imamura… - Current Biology, 2018 - cell.com
For cell division, negatively charged chromatin, in which nucleosome fibers (10 nm fibers)
are irregularly folded [1–5], must be condensed into chromosomes and segregated. While …

Chromatin compaction under mixed salt conditions: opposite effects of sodium and potassium ions on nucleosome array folding

A Allahverdi, Q Chen, N Korolev, L Nordenskiöld - Scientific reports, 2015 - nature.com
It is well known that chromatin structure is highly sensitive to the ionic environment.
However, the combined effects of a physiologically relevant mixed ionic environment of K+ …

Perturbations in nucleosome structure from heavy metal association

K Mohideen, R Muhammad, CA Davey - Nucleic acids research, 2010 - academic.oup.com
Heavy metals have the potential to engage in strong bonding interactions and can thus
function in essential as well as toxic or therapeutic capacities. We conducted …

Magnesium and the control of cell proliferation: looking for a needle in a haystack

FI Wolf, V Trapani, A Cittadini - Magnesium research, 2008 - jle.com
Experimental evidence supports the important role of magnesium in the process of cellular
proliferation, even though cell magnesium homeostasis is not completely clarified. We were …

Magnesium and cell cycle control: an update.

GM Walker - Magnesium, 1986 - europepmc.org
Accumulating evidence, from bacteria to human cells, points to a universal role for
magnesium in controlling the cell cycle. In microorganisms, the co-ordinate sequence of …

Role of magnesium in genomic stability

A Hartwig - … research/fundamental and molecular mechanisms of …, 2001 - Elsevier
In cellular systems, magnesium is the second most abundant element and is involved in
basically all metabolic pathways. At physiologically relevant concentrations, magnesium …

Magnesium homeostasis in mammalian cells

AMP Romani - Metallomics and the Cell, 2013 - Springer
Magnesium, the second most abundant cation within the cell, plays an important role in
numerous biological functions. Experimental evidence indicates that mammalian cells tightly …