The measurement of patient-reported outcomes, including health-related quality of life, is a
new initiative which has emerged and grown over the past four decades. Following the …

Although quality of life assessments have been employed successfully in descriptive and
evaluative studies in oncology, their use in cancer clinical trials has, to date, been limited. A …

PURPOSE Measurement of health-related quality of life (HQL) is becoming more common in
oncology, particularly in clinical trials. The purpose of this report is to review our progress …

Background In cancer clinical trials, the standard end points include response rates,
progression free and overall survival, toxicity. These evaluation criteria do not measure how …

" Quality of Life" is rapidly becoming part of the clinical evaluation process, both as a specific
outcome measure in formal clinical trials, and as a bedside concept. This paper provides an …

The diagnosis and management of cancer can have a major impact on every aspect of a
patient's quality of life. Despite its importance, quality of life is rarely a reported outcome in …

Efforts have recently been mounted to introduce subjective or" quality of life" parameters as
an integral part of the evaluation process in clinical cancer research. While there is no …

Over the past 20 years, changes within medicine and Society have encouraged an
expansion in conceptualizing and evaluating the goals and important outcomes of medical …

Quality of life is a subjective multidimentional concept that can be assessed by means of
validated questionnaires completed by patients. The psychological effects of a diagnosis of …

Over the past 30 years, quality of life has evolved into a respected construct for evaluating
the effectiveness of treatment in health care. The field has grown in methodological rigor and …