Tumor microenvironment (TME) consisting of distinct cell types including stromal cells and
immune cells has recently emerged as a pivotal player in tumor development and …

Accumulating evidence indicate that macrophages activate mesenchymal stem cells (MSCs)
to acquire pro-inflammatory phenotype. However, the role of MSCs activated by …

Resident macrophages in the tumor microenvironment exert a dual role in tumor
progression. So far, the mechanism of intratumoral macrophage generation is still largely …

Mesenchymal stem cells (MSCs) were reported to have strong immunomodulatory ability,
and inhibit the proliferation of T cells and their immune response through cell-to-cell …

Tumor progression depends on the collaborative interactions between tumor cells and the
surrounding stroma. First-line therapies direct against cancer cells may not reach a …

Mesenchymal stem cells (MSCs), which are a kind of stem cell, possess an immune
privileged nature, tumour homing features, and multi-lineage differentiation ability. MSCs …

The majority of premalignant gastric lesions develop in the mucosa that has been modified
by chronic inflammation. As components of the gastritis microenvironment, mesenchymal …

Emerging evidence indicate that mesenchymal stem cells (MSCs) affect tumor progression
by reshaping the tumor microenvironment. Neutrophils are essential component of the tumor …

Mesenchymal stem cells (MSCs) have been shown to integrate into the tumor stroma;
however, the precise mechanisms of this process are still elusive. In this study, the EMT …

Cancer development and progression is linked to tumor-associated macrophages (TAMs).
Distinct TAMs subsets perform either protective or pathogenic effects in cancer. A protective …