Progressive hypoxia: a pivotal pathophysiologic mechanism of COVID-19 pneumonia

VK Somers, T Kara, J Xie - Mayo Clinic Proceedings, 2020 - mayoclinicproceedings.org
Coronavirus disease 2019 (COVID-19) infection has been linked to a broad range of organ
involvement including lungs, heart and blood vessels, and gastrointestinal tract. 1 The most …

Hypoxia in COVID-19: sign of severity or cause for poor outcomes

KB Kashani - Mayo Clinic Proceedings, 2020 - mayoclinicproceedings.org
In December 2019, reports of an outbreak of an unusual viral pneumonia were released
from Wuhan, China, which was later found to be due to infection with novel severe acute …

Silent hypoxia in COVID-19 pneumonia: state of knowledge, pathophysiology, mechanisms, and management

RJM Cajanding - AACN Advanced Critical Care, 2022 - AACN
Patients with COVID-19 often present with life-threatening hypoxemia without dyspnea or
signs of respiratory distress. Termed silent or happy hypoxia, it has puzzled clinicians and …

Pathophysiology of hypoxemia in COVID-19 lung disease

KE Swenson, CC Hardin - Clinics in Chest Medicine, 2023 - chestmed.theclinics.com
From the beginning of the pandemic, the diagnosis and management of hypoxemia has
been an essential aspect of coronavirus disease 2019 (COVID-19) care. Within the first 2 …

Why COVID-19 silent hypoxemia is baffling to physicians

MJ Tobin, F Laghi, A Jubran - … journal of respiratory and critical care …, 2020 - atsjournals.org
Patients with coronavirus disease (COVID-19) are described as exhibiting oxygen levels
incompatible with life without dyspnea. The pairing—dubbed happy hypoxia but more …

Association between hypoxemia and mortality in patients with COVID-19

J Xie, N Covassin, Z Fan, P Singh, W Gao, G Li… - Mayo Clinic …, 2020 - Elsevier
Objective To identify markers associated with in-hospital death in patients with coronavirus
disease 2019 (COVID-19)–associated pneumonia. Patients and Methods A retrospective …

Misconceptions of pathophysiology of happy hypoxemia and implications for management of COVID-19

MJ Tobin, A Jubran, F Laghi - Respiratory research, 2020 - Springer
In the article “The pathophysiology of 'happy'hypoxemia in COVID-19,” Dhont et al.(Respir
Res 21: 198, 2020) discuss pathophysiological mechanisms that may be responsible for the …

[HTML][HTML] Hypoxemia and cytokine storm in COVID-19: clinical implications

C Machado-Curbelo, A González-Quevedo - MEDICC review, 2022 - SciELO Public Health
One of the most dreadful complications that can occur during the course of COVID-19 is the
cytokine storm—also known as cytokine release syndrome—a form of systemic inflammatory …

[HTML][HTML] COVID-19 with silent hypoxemia

W Ottestad, M Seim, JO Mæhlen - Tidsskrift for Den norske …, 2020 - tidsskriftet.no
Discussion The first sign of serious disease in patients with coronavirus infection is usually
pneumonia with respiratory failure, and data from China show that the majority do not …

Silent Hypoxia in Coronavirus disease-2019: Is it more dangerous?-A retrospective cohort study

P Sirohiya, A Elavarasi, HKR Sagiraju, M Baruah… - Lung India, 2022 - journals.lww.com
Background: Hypoxia in patients with COVID-19 is one of the strongest predictors of
mortality. Silent hypoxia is characterised by the presence of hypoxia without dyspnoea …