Background The impact of p-cresyl sulfate (PCS) and indoxyl sulfate (IS) on the prognosis of
patients with uremia remains controversial. We performed a prospective study on peritoneal …

Background/Aims. Previous studies have reported p‐cresyl sulfate (PCS) was related to
endothelial dysfunction and adverse clinical effect. We investigate the adverse effects of …

Background. The mortality rate of elderly hemodialysis (HD) patients is high. Serum p-cresyl
sulfate (PCS) and indoxyl sulfate (IS) are associated with cardiovascular (CV) disease and …

Background High serum concentrations of the protein-bound uremic retention solutes p-
cresyl sulfate (PCS) and indoxyl sulfate (IndS) and inflammation are associated with …

Background. Indoxyl sulphate (IS) and p-cresyl sulphate (PCS) are uraemic toxins that have
similar protein binding, dialytic clearance and proinflammatory features. However, only a few …

Background Accumulating evidence supports the important role of protein-bound uremic
toxins such as indoxyl sulfate and p-cresol in uremic syndrome. They exert direct deleterious …

Abstract Background and Aims Uremic toxins are markedly accumulated in chronic kidney
disease (CKD) patients. Among these two protein-bound compounds, indoxyl sulfate (IXS) …

Results: Univariate Cox proportional hazard ratio analysis revealed that cardiovascular
events were associated with gender (p= 0.02), diabetes (p< 0.01), calcium (p= 0.01), total …

Background Indoxyl sulfate (IS) and p-cresyl sulfate (PCS) are protein-bound uremic toxins
that increase in the sera of patients with chronic kidney disease (CKD), and are not …

The uremic syndrome is attributed to progressive retention of compounds that, under normal
conditions, are excreted by the healthy kidneys. p-cresol sulfate (PCS), a prototype protein …