HLA has strongest association with IgA nephropathy in genome-wide analysis

J Feehally, M Farrall, A Boland, DP Gale… - Journal of the …, 2010 - journals.lww.com
Demographic and family studies support the existence of a genetic contribution to the
pathogenesis of IgA nephropathy, but results from genetic association studies of candidate …

The genetics of IgA nephropathy

I Beerman, J Novak, RJ Wyatt, BA Julian… - Nature clinical practice …, 2007 - nature.com
IgA nephropathy is the most common form of primary glomerulonephritis. Variations in
clinical manifestations indicate that a diagnosis of IgA nephropathy encompasses multiple …

Genome-wide association study identifies susceptibility loci for IgA nephropathy

AG Gharavi, K Kiryluk, M Choi, Y Li, P Hou, J Xie… - Nature …, 2011 - nature.com
We carried out a genome-wide association study of IgA nephropathy, a major cause of
kidney failure worldwide. We studied 1,194 cases and 902 controls of Chinese Han …

[HTML][HTML] Genetic heterogeneity in Italian families with IgA nephropathy: suggestive linkage for two novel IgA nephropathy loci

L Bisceglia, G Cerullo, P Forabosco, DD Torres… - The American Journal of …, 2006 - cell.com
IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide, but its etiologic
mechanisms are still poorly understood. Different prevalences among ethnic groups and …

Genetic studies of IgA nephropathy: past, present, and future

K Kiryluk, BA Julian, RJ Wyatt, F Scolari, H Zhang… - Pediatric …, 2010 - Springer
Immunoglobulin A nephropathy (IgAN) is the most common form of primary
glomerulonephritis worldwide and an important cause of kidney disease in young adults …

Genome-wide meta-analysis identifies three novel susceptibility loci and reveals ethnic heterogeneity of genetic susceptibility for IgA nephropathy

M Li, L Wang, DC Shi, JN Foo, Z Zhong… - Journal of the …, 2020 - journals.lww.com
Background Eighteen known susceptibility loci for IgAN account for only a small proportion
of IgAN risk. Methods Genome-wide meta-analysis was performed in 2628 patients and …

The pathophysiology of IgA nephropathy

H Suzuki, K Kiryluk, J Novak… - Journal of the …, 2011 - journals.lww.com
Here we discuss recent advances in understanding the biochemical, immunologic, and
genetic pathogenesis of IgA nephropathy, the most common primary glomerulonephritis …

Genome-wide linkage scan of a large family with IgA nephropathy localizes a novel susceptibility locus to chromosome 2q36

AD Paterson, XQ Liu, K Wang… - Journal of the …, 2007 - journals.lww.com
IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide and an important
cause of ESRD. Familial clustering of cases suggests genetic predisposition to this disease …

[HTML][HTML] Evidence for genetic factors in the development and progression of IgA nephropathy

I Stephen, H Hsu, SB Ramirez, MP Winn… - Kidney international, 2000 - Elsevier
Evidence for genetic factors in the development and progression of IgA nephropathy.
Background IgA nephropathy (IgAN) is the most common glomerulonephritis in the world …

[HTML][HTML] Identification of new susceptibility loci for IgA nephropathy in Han Chinese

M Li, JN Foo, JQ Wang, HQ Low, XQ Tang… - Nature …, 2015 - nature.com
IgA nephropathy (IgAN) is one of the most common primary glomerulonephritis. Previously
identified genome-wide association study (GWAS) loci explain only a fraction of disease risk …