Developments in scalable strategies for detecting early markers of cognitive decline

R Whelan, FM Barbey, MR Cominetti, CM Gillan… - Translational …, 2022 - nature.com
Effective strategies for early detection of cognitive decline, if deployed on a large scale,
would have individual and societal benefits. However, current detection methods are …

Mobile technologies in the early detection of cognitive decline

M Allard, M Husky, G Catheline, A Pelletier… - PloS one, 2014 - journals.plos.org
The identification of biological and pathophysiological processes implicated in different
forms of dementia is itself dependent on reliable descriptions of cognitive performance and …

Early detection of neurodegenerative disorders using behavioral markers and new technologies: New methods and perspectives

V Manera, E Rovini, P Wais - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Neurodegenerative disorders (ND) are a common cause of mortality and morbidity
worldwide, particularly in older people. As life spans continue to increase, the incidence of …

Innovative diagnostic tools for early detection of Alzheimer's disease

C Laske, HR Sohrabi, SM Frost, K López-de-Ipiña… - Alzheimer's & …, 2015 - Elsevier
Current state-of-the-art diagnostic measures of Alzheimer's disease (AD) are invasive
(cerebrospinal fluid analysis), expensive (neuroimaging) and time-consuming …

Feasibility of repeated assessment of cognitive function in older adults using a wireless, mobile, dry-EEG headset and tablet-based games

EC McWilliams, FM Barbey, JF Dyer, MN Islam… - Frontiers in …, 2021 - frontiersin.org
Access to affordable, objective and scalable biomarkers of brain function is needed to
transform the healthcare burden of neuropsychiatric and neurodegenerative disease …

Neuropsychological decline improves prediction of dementia beyond Alzheimer's disease biomarker and mild cognitive impairment diagnoses

DA Nation, JK Ho, S Dutt, SD Han… - Journal of …, 2019 - content.iospress.com
Background: A clinical diagnosis of cognitive impairment is traditionally based on a single
cognitive exam, but serial cognitive testing can be sensitive to subtle cognitive changes in …

Assessing the progression of mild cognitive impairment to Alzheimer's disease: current trends and future directions

LG Brooks, DA Loewenstein - Alzheimer's research & therapy, 2010 - Springer
With the advent of advances in biomarker detection and neuropsychological measurement,
prospects have improved for identifying and tracking the progression of Alzheimer's disease …

Assessment of cognition in mild cognitive impairment: a comparative study

PJ Snyder, CE Jackson, RC Petersen… - Alzheimer's & …, 2011 - Elsevier
The demand for rapidly administered, sensitive, and reliable cognitive assessments that are
specifically designed for identifying individuals in the earliest stages of cognitive decline …

Early indications of future cognitive decline: stable versus declining controls

A Rizk-Jackson, P Insel, R Petersen, P Aisen, C Jack… - PloS one, 2013 - journals.plos.org
This study aimed to identify baseline features of normal subjects that are associated with
subsequent cognitive decline. Publicly available data from the Alzheimer's Disease …

Intraindividual cognitive decline using a brief computerized cognitive screening test

DG Darby, RH Pietrzak, J Fredrickson… - Alzheimer's & …, 2012 - Elsevier
BACKGROUND: Progressive intraindividual decline in memory and cognition is
characteristic of dementia and may be useful in detecting very early Alzheimer's disease …