Cartilage degeneration is among the fundamental reasons behind disability and pain across
the globe. Numerous approaches have been employed to treat cartilage diseases …

Articular cartilage is a load-bearing tissue that lines the surface of bones in diarthrodial
joints. Unfortunately, this avascular tissue has a limited capacity for intrinsic repair …

Repairing or replacing damaged human tissues has been the ambitious goal of
regenerative medicine for over 25 years. One promising approach is the use of hydrated …

Injectable hydrogels have been employed extensively as versatile materials for cartilage
regeneration due to their excellent biocompatibility, tunable structure, and ability to …

Stem cell injections for the treatment of articular cartilage damage are a promising approach
to achieve tissue regeneration. However, this method is encumbered by high cell apoptosis …

Articular cartilage is an important load-bearing tissue distributed on the surface of
diarthrodial joints. Due to its avascular, aneural and non-lymphatic features, cartilage has …

Despite tremendous advances in the field of regenerative medicine, it still remains
challenging to repair the osteochondral interface and full-thickness articular cartilage …

The key to regenerative medicine is in situ regeneration of lesion cells, so as to achieve
lesion repair and regeneration. However, the complex environment of the joint cavity where …

Cartilage regeneration and repair remain a clinical challenge due to the limited capability of
cartilage to self-regenerate. Worldwide, the costs associated with cartilage regeneration per …

Tissue engineering has become a promising strategy for repairing damaged cartilage and
bone tissue. Among the scaffolds for tissue-engineering applications, injectable hydrogels …