Exosomes of mesenchymal stem cells as a proper vehicle for transfecting miR‐145 into the breast cancer cell line and its effect on metastasis

M Sheykhhasan, N Kalhor… - BioMed Research …, 2021 - Wiley Online Library
Background. Despite recent advances in scientific knowledge and clinical practice,
management, and treatment of breast cancer, as one of the leading causes of female …

Delivery of miR-381-3p mimic by mesenchymal stem cell-derived exosomes inhibits triple negative breast cancer aggressiveness; an in vitro study

S Shojaei, SM Hashemi, H Ghanbarian… - Stem cell reviews and …, 2021 - Springer
Recent investigations have emphasized the role of aberrant expression of microRNAs
(miRNAs) in progression of almost all types of cancers. Exosomes, membrane-enclosed …

Exosome-mediated delivery of functionally active miRNA-142-3p inhibitor reduces tumorigenicity of breast cancer in vitro and in vivo

Z Naseri, RK Oskuee, MR Jaafari… - International journal …, 2018 - Taylor & Francis
Background Exosomes, widely recognized natural nanovesicles, represent one of the
recently discovered modes of intercellular communication due to their ability to transmit …

Delivery of LNA-antimiR-142-3p by mesenchymal stem cells-derived exosomes to breast cancer stem cells reduces tumorigenicity

Z Naseri, RK Oskuee… - Stem cell reviews and …, 2020 - Springer
Exosomes, nano-sized cell-derived vesicles, have been employed as non-synthetic carriers
of various pharmaceutics in numerous studies. As higher expression levels of miR-142-3p …

Evaluating the influence of Human Umbilical Cord Mesenchymal Stem Cells-derived exosomes loaded with miR-3182 on metastatic performance of Triple Negative …

Y Khazaei-Poul, S Shojaei, A Koochaki, H Ghanbarian… - Life sciences, 2021 - Elsevier
Abstract Aims Deregulation of microRNA (miRNA) function has been linked to numerous
human cancers, such as Triple Negative Breast Cancer (TNBC). Exosomes, a subgroup of …

Exosomes derived from miR-34a-overexpressing mesenchymal stem cells inhibit in vitro tumor growth: A new approach for drug delivery

F Vakhshiteh, S Rahmani, SN Ostad, Z Madjd… - Life Sciences, 2021 - Elsevier
Aims Exosomes hold great promise as bio-inspired delivery vehicles. Mesenchymal stem
cells (MSCs) are recognized for their potential to yield huge quantities of exosomes. We …

MicroRNA-100 shuttled by mesenchymal stem cell-derived exosomes suppresses in vitro angiogenesis through modulating the mTOR/HIF-1α/VEGF signaling axis in …

K Pakravan, S Babashah, M Sadeghizadeh, SJ Mowla… - Cellular oncology, 2017 - Springer
Background Human mesenchymal stem cells (MSCs) have been shown to be involved in
the formation and modulation of tumor stroma and in interacting with tumor cells, partly …

Mesenchymal stem cell-derived exosome mir-342-3p inhibits metastasis and chemo-resistance of breast cancer through regulating ID4

S Yu, Y Zhou, L Niu, Y Qiao, Y Yan - Genes & genomics, 2022 - Springer
Background The mesenchymal stem cell-derived exosome (MSCs-exo) carrying microRNAs
have been proved to regulate tumor biological activities. Clarifying molecular mechanism …

[HTML][HTML] Mesenchymal stem cell-derived exosomes as new tools for delivery of miRNAs in the treatment of cancer

A Dalmizrak, O Dalmizrak - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Although ongoing medical research is working to find a cure for a variety of cancers, it
continues to be one of the major causes of death worldwide. Chemotherapy and …

[HTML][HTML] Mesenchymal stem cell-derived exosomes carrying microRNA-150 suppresses the proliferation and migration of osteosarcoma cells via targeting IGF2BP1

Z Xu, X Zhou, J Wu, X Cui, M Wang… - Translational cancer …, 2020 - ncbi.nlm.nih.gov
Background MicroRNA-150 (miR-150) plays a critical role in varied types of human cancers.
In this study, we explored the effect and mechanism of mesenchymal stem cell (MSC) …