Response to methylphenidate is not influenced by DAT1 polymorphisms in a sample of Brazilian adult patients with ADHD

V Contini, MM Victor, FZC Marques, GP Bertuzzi… - Journal of neural …, 2010 - Springer
Several lines of evidence suggest a relevant role for the dopamine transporter (DAT1) gene
not only as a susceptibility factor for attention-deficit hyperactivity disorder (ADHD), but also …

A common haplotype at the dopamine transporter gene 5′ region is associated with attention‐deficit/hyperactivity disorder

JP Genro, GV Polanczyk, C Zeni… - American Journal of …, 2008 - Wiley Online Library
The dopamine transporter (DAT) is the major site of methylphenidate action, which is one of
the main drugs used to treat attention‐deficit/hyperactivity disorder (ADHD). Most …

Dopamine transporter gene, response to methylphenidate and cerebral blood flow in attention‐deficit/hyperactivity disorder: A pilot study

LA Rohde, T Roman, C Szobot, RD Cunha, MH Hutz… - Synapse, 2003 - Wiley Online Library
The homozygosity of the 10‐repeat allele at dopamine transporter gene (DAT1) seems to be
associated with a poor response to methylphenidate (MPH) in children with attention …

Absence of association with DAT1 polymorphism and response to methylphenidate in a sample of adults with ADHD

E Mick, J Biederman, T Spencer… - American Journal of …, 2006 - Wiley Online Library
A polymorphism in the dopamine transporter gene (DAT1) has been previously associated
with ADHD and methylphenidate has been hypothesized to block the dopamine transporter …

Association of the 480 bp DAT1 allele with methylphenidate response in a sample of Irish children with ADHD

A Kirley, N Lowe, Z Hawi, C Mullins… - American Journal of …, 2003 - Wiley Online Library
Several studies have implicated the dopamine transporter gene (DAT1) as conferring
susceptibility to attention deficit hyperactivity disorder (ADHD), in particular, a VNTR situated …

[HTML][HTML] Dopamine transporter genotype and methylphenidate dose response in children with ADHD

MA Stein, ID Waldman, CS Sarampote… - …, 2005 - nature.com
Stimulant medications, such as methylphenidate (MPH), are the most commonly used,
effective treatment for ADHD. MPH acts primarily by inhibiting the dopamine transporter …

Dopamine transporter gene and response to methylphenidate in attention-deficit/hyperactivity disorder

T Roman, C Szobot, S Martins… - Pharmacogenetics …, 2002 - journals.lww.com
This study aims to evaluate whether a previously reported association between
homozygosity for the 10-repeat allele of the dopamine transporter gene (10/10) and poor …

Dopamine transporter genotype and stimulant side effect factors in youth diagnosed with attention-deficit/hyperactivity disorder

R Gruber, R Joober, N Grizenko… - Journal of Child and …, 2009 - liebertpub.com
The dopamine transporter locus (DAT1) has been studied as a risk factor for attention-
deficit/hyperactivity disorder (ADHD) and in pharmacogenetic studies of stimulant response …

Polymorphisms of the dopamine transporter gene: influence on response to methylphenidate in attention deficit-hyperactivity disorder

T Roman, LA Rohde, MH Hutz - American Journal of Pharmacogenomics, 2004 - Springer
Attention deficit-hyperactivity disorder (ADHD) is a very common and heterogeneous
childhood-onset psychiatric disorder, affecting between 3% and 5% of school age children …

A promoter polymorphism (− 839 C> T) at the dopamine transporter gene is associated with attention deficit/hyperactivity disorder in Brazilian children

JP Genro, C Zeni, GV Polanczyk… - American Journal of …, 2007 - Wiley Online Library
The dopamine transporter (DAT) plays a key role in the regulation of dopaminergic
neurotransmission and is also the major site of action for methylphenidate which is one of …