Prognostic value of EMT gene signature in malignant mesothelioma

L Wu, K Yoshihara, H Yun, S Karim, N Shokri… - International Journal of …, 2023 - mdpi.com
Malignant mesothelioma (MESO) consists of epithelioid, biphasic, and sarcomatoid
subtypes with different epithelial–mesenchymal transition (EMT) phenotypes. We previously …

A panel of emerging EMT genes identified in malignant mesothelioma

L Wu, S Amjad, H Yun, S Mani, M de Perrot - Scientific reports, 2022 - nature.com
Malignant mesothelioma (MESO) is a highly aggressive cancer with poor prognosis.
Epithelial–mesenchymal transition (EMT) is a critical process in malignancies involved in …

COL1A1 is a potential prognostic biomarker and correlated with immune infiltration in mesothelioma

C Zhang, S Liu, X Wang, H Liu… - BioMed Research …, 2021 - Wiley Online Library
Objective. Mesothelioma (MESO) is a rare tumor derived from mesothelium cells. The aim of
this study was to explore key candidate genes and potential molecular mechanisms for …

A gene signature linked to fibroblast differentiation for prognostic prediction of mesothelioma

J Liu, Y Lu, Y Liu, W Zhang, S Xian, S Wang, Z Zheng… - Cell & Bioscience, 2024 - Springer
Background Malignant mesothelioma is a type of infrequent tumor that is substantially
related to asbestos exposure and has a terrible prognosis. We tried to produce a fibroblast …

Molecular classification of malignant pleural mesothelioma: identification of a poor prognosis subgroup linked to the epithelial-to-mesenchymal transition

A De Reynies, MC Jaurand, A Renier, G Couchy… - Clinical Cancer …, 2014 - AACR
Purpose: Despite research efforts to develop more effective diagnostic and therapeutic
approaches, malignant pleural mesothelioma (MPM) prognosis remains poor. The …

[HTML][HTML] Genomic and transcriptomic analyses identify a prognostic gene signature and predict response to therapy in pleural and peritoneal mesothelioma

NU Nair, Q Jiang, JS Wei, VA Misra, B Morrow… - Cell Reports …, 2023 - cell.com
Malignant mesothelioma is an aggressive cancer with limited treatment options and poor
prognosis. A better understanding of mesothelioma genomics and transcriptomics could …

Molecular characterization of mesothelioma: impact of histologic type and site of origin on molecular landscape

I Dagogo-Jack, RW Madison, JK Lennerz… - JCO Precision …, 2022 - ascopubs.org
PURPOSE Mesothelioma is an aggressive malignancy with heterogeneous outcomes that
are partly driven by the differential efficacy of existing therapies across histologic types and …

Tumor microenvironment-associated immune-related genes for the prognosis of malignant pleural mesothelioma

X Xu, L Cheng, Y Fan, W Mao - Frontiers in Oncology, 2020 - frontiersin.org
Malignant pleural mesothelioma (MPM) is a rare but highly aggressive thoracic malignancy.
ESTIMATE algorithm-derived immune scores are commonly used to quantify the immune …

Aurora kinase a as a diagnostic and prognostic marker of malignant mesothelioma

Z Guo, L Shen, N Li, X Wu, C Wang, Z Gu… - Frontiers in …, 2021 - frontiersin.org
Background Malignant mesothelioma (MM) is a highly aggressive cancer with a poor
prognosis. Despite the use of several well-known markers, the diagnosis of MM is still …

Define the two molecular subtypes of epithelioid malignant pleural mesothelioma

UAK Saddozai, F Wang, S Khattak, MU Akbar, M Badar… - Cells, 2022 - mdpi.com
Malignant pleural mesothelioma (MPM) is a fatal disease of respiratory system. Despite the
availability of invasive biomarkers with promising results, there are still significant diagnostic …