Dedifferentiated Chondrosarcoma from Molecular Pathology to Current Treatment and Clinical Trials

W Zając, J Dróżdż, W Kisielewska, W Karwowska… - Cancers, 2023 - mdpi.com
Simple Summary Dedifferentiated chondrosarcoma is a rare type of cancer that is very
aggressive and has a poor prognosis with poor survival rates. This disease can affect …

A retrospective multi-institutional cohort analysis of clinical characteristics and outcomes in dedifferentiated chondrosarcoma

N Bui, H Dietz, S Farag, AC Hirbe, MJ Wagner… - Cancers, 2023 - mdpi.com
Simple Summary Dedifferentiated chondrosarcoma (DDCS) is a rare cancer that is
aggressive and leads to high patient mortality. There are limited data on the efficacy of …

Dedifferentiated chondrosarcoma demonstrating osteosarcomatous differentiation

BS Dhinsa, M DeLisa, R Pollock… - Oncology Research …, 2018 - karger.com
Background: Dedifferentiated chondrosarcoma (DDC) accounts for a small proportion of
chondrosarcomas. They demonstrate aggressive behaviour with a high rate of local …

Dedifferentiated Chondrosarcoma: Diagnostic Controversies and Emerging Therapeutic Targets

M El Beaino, ST Hoda, AJ Eldeib, K Masrouha - Current Oncology Reports, 2023 - Springer
Abstract Purpose of Review The pathogenesis of dedifferentiated chondrosarcoma is
controversial, and no genetic abnormality has consistently been identified in the disease …

Dedifferentiated chondrosarcoma: current standards of care

AK Kattepur, RL Jones, A Gulia - Future Oncology, 2021 - Future Medicine
Dedifferentiated chondrosarcomas are aggressive variants of chondrosarcoma, associated
with poor outcomes. Tumor biphasism is the norm. The majority of these tumors are …

Prognostic factors in dedifferentiated chondrosarcoma: a retrospective analysis of a large series treated at a single institution

R Miao, E Choy, KA Raskin, JH Schwab, GP Nielsen… - Sarcoma, 2019 - Wiley Online Library
Background. Dedifferentiated chondrosarcomas (DDCSs) are highly malignant tumors with
a dismal prognosis and present a significant challenge in clinical management. Methods. In …

Dedifferentiated chondrosarcoma: a survival analysis of 159 cases from the SEER database (2001‐2011)

PK Strotman, TJ Reif, SA Kliethermes… - Journal of surgical …, 2017 - Wiley Online Library
Background and Objectives Dedifferentiated chondrosarcoma is a rare malignancy with
reported 5‐year overall survival rates ranging from 7% to 24%. The purpose of this …

[HTML][HTML] Dedifferentiated chondrosarcoma: a case series and review of the literature

CA Gusho, L Lee, A Zavras, Z Seikel, I Miller… - Orthopedic …, 2022 - ncbi.nlm.nih.gov
Background Dedifferentiated chondrosarcoma (DCS) is a rare and aggressive malignancy
with a poor prognosis. The purpose of this investigation was to describe our treatment and …

Dedifferentiated chondrosarcoma—a fatal disease

J Bruns, W Fiedler, M Werner, G Delling - Journal of cancer research and …, 2005 - Springer
Background We report on 13 patients with dedifferentiated chondrosarcomas. The mean
age of the patients at diagnosis was 59.8 years. Nine patients were classified as stage IIB …

A Systematic Review of Adjuvant Chemotherapy in Localized Dedifferentiated Chondrosarcoma

S Tsukamoto, AF Mavrogenis, Y Nitta, A Righi… - Current …, 2024 - mdpi.com
Dedifferentiated chondrosarcoma (DDCS) is a high-grade subtype of chondrosarcoma with
the bimorphic histological appearance of a conventional chondrosarcoma component with …