The bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs) can be
improved via the formulation of an amorphous solid dispersion (ASD), where the API is …

The development of an amorphous solid dispersion (ASD) is a promising strategy for
improving the low bioavailability of many poorly water-soluble active pharmaceutical …

Knowing the solubilities of active pharmaceutical ingredients (APIs) in pure solvents and
solvent mixtures is essential for several manufacturing aspects of pharmaceutical product …

In this work we investigated the solubilities of 10 active pharmaceutical ingredients (APIs),
namely, fenofibrate, ibuprofen, cinnarizine, carbamazepine, indomethacin, naproxen …

For the solubility and bioavailability of poorly soluble active pharmaceutical ingredients
(APIs) to be improved, the transformation of crystalline APIs to the amorphous state has often …

Computational modeling is of great importance in solvent selection for new active
pharmaceutical ingredients (APIs), with the Perturbed-Chain Statistical Associating Fluid …

To improve the bioavailability of poorly soluble active pharmaceutical ingredients (APIs),
these materials are often integrated into a polymer matrix that acts as a carrier. The resulting …

A pair of popular thermodynamic models for pharmaceutical applications, namely, the
perturbed-chain statistical associating fluid theory (PC-SAFT) equation of state and the …

A new scheme is presented for the parameterization of pharmaceuticals in the context of the
perturbed-chain statistical associating fluid theory (PC-SAFT). The pharmaceutical …

Prediction of compatibility of the active pharmaceutical ingredient (API) with the polymeric
carrier plays an essential role in designing drug delivery systems and estimating their long …