New insights on trehalose: a multifunctional molecule

AD Elbein, YT Pan, I Pastuszak, D Carroll - Glycobiology, 2003 - academic.oup.com
Trehalose is a nonreducing disaccharide in which the two glucose units are linked in an α, α-
1, 1-glycosidic linkage. This sugar is present in a wide variety of organisms, including …

Physiological roles of trehalose in bacteria and yeasts: a comparative analysis

JC Argüelles - Archives of microbiology, 2000 - Springer
The disaccharide trehalose is widely distributed in nature and can be found in many
organisms, including bacteria, fungi, plants, invertebrates and mammals. Due to its particular …

Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex

W Bell, W Sun, S Hohmann, S Wera, A Reinders… - Journal of biological …, 1998 - ASBMB
In the yeast Saccharomyces cerevisiae, trehalose-6-phosphate synthase (TPS) and
trehalose-6-phosphate phosphatase (TPP), which convert glucose 6-phosphate plus UDP …

Trehalose metabolism: from osmoprotection to signaling

G Iturriaga, R Suárez, B Nova-Franco - International journal of molecular …, 2009 - mdpi.com
Trehalose is a non-reducing disaccharide formed by two glucose molecules. It is widely
distributed in Nature and has been isolated from certain species of bacteria, fungi …

The importance of a functional trehalose biosynthetic pathway for the life of yeasts and fungi

C Gancedo, CL Flores - FEMS Yeast Research, 2004 - academic.oup.com
The view of the role of trehalose in yeast has changed in the last few years. For a long time
considered a reserve carbohydrate, it gained new importance when its function in the …

Revisiting yeast trehalose metabolism

E Eleutherio, A Panek, JF De Mesquita, E Trevisol… - Current genetics, 2015 - Springer
Establishing the function of trehalose in yeast cells has led us, over the years, through a long
path—from simple energy storage carbohydrate, then a stabilizer and protector of …

Trehalose synthase: guard to the gate of glycolysis in yeast?

JM Thevelein, S Hohmann - Trends in biochemical sciences, 1995 - cell.com
The addition of glucose to cells of the yeast Saccharomyces cerevisiae triggers a variety of
regulatory phenomena. Initial glucose metabolism is required for the induction of most of …

The control of trehalose biosynthesis in Saccharomyces cerevisiae: Evidence for a catabolite inactivation and repression of trehalose‐6‐phosphate synthase and …

J François, MJ Neves, HG Hers - Yeast, 1991 - Wiley Online Library
During diauxic growth of yeast in glucose‐rich medium, the accumulation of trehalose
started well after complete exhaustion of glucose from the medium. The accumulation of the …

The donor subsite of trehalose-6-phosphate synthase: binary complexes with UDP-glucose and UDP-2-deoxy-2-fluoro-glucose at 2 Å resolution

RP Gibson, CA Tarling, S Roberts, SG Withers… - Journal of Biological …, 2004 - ASBMB
Trehalose is an unusual non-reducing disaccharide that plays a variety of biological roles,
from food storage to cellular protection from environmental stresses such as desiccation …

The function of trehalose biosynthesis in plants

A Wingler - Phytochemistry, 2002 - Elsevier
Trehalose (α-d-glucopyranosyl-1, 1-α-d-glucopyranoside) occurs in a large variety of
organisms, ranging from bacteria to invertebrate animals, where it serves as an energy …